929016-74-0Relevant articles and documents
Studies on the synthesis and antiproliferative activities of 13-cis-retinoyl sugar derivatives
Xiang, Jian-Nan,Jiang, Li-Hui,Chen, Chao-Yue,Fu, Zhi-Ying,Duan, Jun-Fei,He, Xiao-Xiao,Wang, Ke-Min
, p. 595 - 614 (2007/10/03)
New retinoyl sugar derivatives of 13-cis-retinoic acid were synthesized in three ways in this paper in order to enhance pharmacal effects, especially antiproliferative activities of 13-cis-retinoic acid. Their structures were confirmed by IR, 1H-NMR, 13C-NMR, and MS spectra and their antiproliferative activities were determined in vitro using human cancer lines. Results showed that some compounds possessed potential antitumor activities. Copyright Taylor & Francis Group, LLC.