929608-16-2Relevant articles and documents
Scalable synthesis of a cis-substituted cyclobutyl-benzothiazole pyridazinone: Process development of an efficient copper catalyzed C-N cross-coupling reaction
Kallemeyn, Jeffrey M.,Ku, Yi-Yin,Mulhern, Mathew M.,Bishop, Richard,Pal, Agnes,Jacob, Legi
, p. 191 - 197 (2014)
A scalable process for the preparation of 2-(2-(cis-3-(piperidin-1-yl) cyclobutyl)benzothiazol-6-yl)pyridazin- 3(2H)-one in multi-kilogram amounts and in high purity has been developed. The key features of this synthesis are the coppercatalyzed C-N cross-