92976-55-1

Basic information

• Product Name: Silane, (1,1-dimethylethyl)[[4-(1,1-dimethylethyl)cyclohexyl]oxy]dimethyl-
• CAS NO: 92976-55-1
• Molecular Formula: C16H34OSi
• Molecular Weight: 270.531
• Mol File: 92976-55-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)[[4-(1,1-dimethylethyl)cyclohexyl]oxy]dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)[[4-(1,1-dimethylethyl)cyclohexyl]oxy]dimethyl-(92976-55-1)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)[[4-(1,1-dimethylethyl)cyclohexyl]oxy]dimethyl-(92976-55-1)

Safety Data

• Hazardous Substances Data: 92976-55-1(Hazardous Substances Data)

Upstream product

• 98-52-2 4-(1,1-dimethylethyl)-cyclohexanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 68039-42-9 4-t-butylcyclohexyl formate 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 80356-16-7 2-(4-tert-Butyl-cyclohexyloxy)-tetrahydro-pyran 

Downstream Products

• 98-52-2 4-(1,1-dimethylethyl)-cyclohexanol 
• 7080-86-6 1-(tert-butyl)-4-bromocyclohexane 
• 32210-23-4 para-tert-butylcyclohexyl acetate 
• 98-53-3 4-tercbutyl-cyclohexanone 

Relevant articles and documents

One-step conversion of formate esters to O-silyl ethers by means of samarium diiodide in the presence of chlorosilane reagents

One-step conversion of various types of formate esters into the corresponding O-silyl ethers under neutral reaction conditions was established by employing samarium diiodide in the presence of chlorosilane reagents.

Solvent-modulated Pd/C-catalyzed deprotection of silyl ethers and chemoselective hydrogenation

Recently we have reported undesirable and frequent deprotection of the TBDMS protective group of a variety of hydroxyl functions occurred under neutral and mild hydrogenation conditions using 10% Pd/C in MeOH. The deprotection of silyl ethers is susceptible to significant solvent effect. TBDMS and TES protecting groups were selectively cleaved in the presence of acid-sensitive functional groups such as TIPS ether, TBDPS ether and dimethyl acetal under hydrogenation condition using 10% Pd/C in MeOH. In contrast, chemoselective hydrogenation of reducible functional groups such as acetylene, olefin and benzyl ether, proceeds in the presence of TBDMS or TES ethers in AcOEt or MeCN.

A novel method for direct conversion of tetrahydropyranyl ethers into t-butyldimethylsilyl ethers with t-butyldimethylsilyl triflate and dimethyl sulfide

Direct conversion of THP ethers into TBS ethers has been achieved with TBSOTf and dimethyl sulfide in dichloromethane.