929804-33-1Relevant articles and documents
NEW DERIVATIVES OF INDOLE FOR THE TREATMENT OF CANCER, VIRAL INFECTIONS AND LUNG DISEASES
-
Page/Page column 52, (2014/06/24)
The present invention relates to a new class of indole derivatives, having a particular MKlp2 inhibition profile and useful as a therapeutic agent, in particular for the treatment of cancer, viral infections and lung diseases.
Synthesis and SAR of novel 2-arylthiazolidinones as selective analgesic N-type calcium channel blockers
Knutsen, Lars J.S.,Hobbs, Christopher J.,Earnshaw, Christopher G.,Fiumana, Andrea,Gilbert, Jenny,Mellor, Sarah L.,Radford, Fleur,Smith, Nichola J.,Birch, Philip J.,Russell Burley,Ward, Stuart D.C.,James, Iain F.
, p. 662 - 667 (2007/10/03)
A series of new N-type (Cav2.2) calcium channel blockers derived from the 'hit' structures 2-(3-bromo-4-fluorophenyl)-3-(2-pyridin-2-ylethyl)thiazolidin-4-one 9 and its 2-[4-(4-bromophenyl)pyridin-3-yl]-3-isobutyl analogue 10 is described. Exte