93073-22-4

Basic information

• Product Name: 5-(p-Methoxybenzyl)-2-phenyl-s-triazolo(3,4-b)-1,3,4-thiadiazole
• CAS NO: 93073-22-4
• Molecular Weight: 322.39
• Mol File: 93073-22-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 5-(p-Methoxybenzyl)-2-phenyl-s-triazolo(3,4-b)-1,3,4-thiadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(p-Methoxybenzyl)-2-phenyl-s-triazolo(3,4-b)-1,3,4-thiadiazole(93073-22-4)
• EPA Substance Registry System: 5-(p-Methoxybenzyl)-2-phenyl-s-triazolo(3,4-b)-1,3,4-thiadiazole(93073-22-4)

Safety Data

• Hazardous Substances Data: 93073-22-4(Hazardous Substances Data)

Upstream product

• 93073-14-4 4-amino-3-(4-methoxybenzyl)-1H-1,2,4-triazole-5(4H)-thione 
• 65-85-0 benzoic acid 
• 104-01-8 4-Methoxyphenylacetic acid 
• 93073-37-1 5-(4-methoxybenzyl)-4-amino-1,3,4-oxadiazole-2-thiol 
• 93073-14-4 4-amino-3-(p-methoxybenzyl)-5-mercapto-1,2,4-triazole 

Relevant articles and documents

Novel 1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives as dual analgesic/anti-inflammatory and antimicrobial agents

For this study, a series of 3,6-disubstituted-1,2,4-triazolo-[3,4-b]-1,3,4- thiadiazoles (1-12) were synthesized by condensation of 4-amino-5-substituted-3- mercapto-1,2,4-triazoles with various benzoic acids through a one-pot reaction. The anti-inflammatory and analgesic activities as well as gastrointestinal irritation liability of the obtained compounds were evaluated. Several of the synthesized compounds showed noticeable analgesic and anti-inflammatory activity. For the active compounds a very low ulcerogenic index and diminished oxidative damage in stomach were observed. Moreover, title compounds were screened for their antifungal and antibacterial activities. Antifungal activity of the compounds was found better than that of their antibacterial activity.

Synthesis and Pharmacology of 2-Aryl/aralkyl-5-aryl/aralkyl/diaralkyl-s-triazolo-1,3,4-thiadiazoles

A series of s-triazolo-1,3,4-thiadiazoles (III) carrying aryl or aralkyl group at 2-position and aryl, aralkyl or diaralkyl group at 5-position have been synthesised and evaluated for their biological activities.Some of the compounds exhibit strong CNS depressant and mild to moderate antiinflammatory action in experimental animals.