930781-40-1

Basic information

• Product Name: 2-(2,4-dichloroyphenyl)quinoxaline
• Synonyms: 2-(2,4-dichloroyphenyl)quinoxaline
• CAS NO: 930781-40-1
• Molecular Weight: 275.137
• Mol File: 930781-40-1.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-(2,4-dichloroyphenyl)quinoxaline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4-dichloroyphenyl)quinoxaline(930781-40-1)
• EPA Substance Registry System: 2-(2,4-dichloroyphenyl)quinoxaline(930781-40-1)

Safety Data

• Hazardous Substances Data: 930781-40-1(Hazardous Substances Data)

Upstream product

• 2123-27-5 2,4-dichlorostyrene 
• 95-54-5 1,2-diamino-benzene 
• 4252-78-2 2,2',4'-trichloroacetophenone 
• 54484-62-7 2,4-dichloro-1-ethylbenzene 
• 2631-72-3 2,4-dichlorophenacyl bromide 
• 137958-96-4 α-hydroxy(2',4'-dichloro)acetophenone 

Relevant articles and documents

One-Pot Protocol for the Synthesis of Imidazoles and Quinoxalines using N-Bromosuccinimide

N-bromosuccinimide (NBS)-mediated one-pot, green, efficient and practical synthesis of substituted imidazoles and quinoxalines has been achieved by the reaction of styrenes with N-arylbenzamidines and o-phenylenediamines, respectively, in a water:1,4-dioxane mixture. The reaction involves formation of an α-bromo ketone as an intermediate in the presence of NBS and water, followed by condensation with the N-arylbenzamidine and o-phenylenediamine. Use of an inexpensive NBS as a bromine source as well as an oxidant, water as a solvent and readily available starting materials makes this protocol environmentally benign and economically viable. Substituted imidazoles and quinoxalines were obtained in good to excellent yields with wide functional group compatibility. (Figure presented.).

Catalyst-free synthesis of quinoxalines

Quinoxalines are a class of important heterocycles, so to explore a facile and practical new synthetic method is always demanded. We have developed a new catalyst-free domino synthesis of quinoxalines from phenacyl halides and 1,2-diaminoarenes. Phenacyl

Synthesis of functionalized benzimidazoles and quinoxalines catalyzed by sodium hexafluorophosphate bound Amberlite resin in aqueous medium

A very simple, eco-friendly, and versatile method for the selective synthesis of 1,2-disubstituted benzimidazoles and quinoxalines in water-methanol (1:1) mixture with the aid of resin bound hexafluorophosphate ion as catalyst is reported. The method is also effective for the incorporation of quinoxaline nucleus at the A ring of pentacyclic triterpenoid, friedelin. A plausible mechanism for the formation of disubstituted benzimidazole has also been suggested.