93299-38-8

Basic information

• Product Name: L-Tryptophan, 5-bromo-, methyl ester
• Synonyms: 5-bromo-tryptophan methyl ester;5-BROMO-L-TRYPTOPHAN METHYL ESTER
• CAS NO: 93299-38-8
• Molecular Formula: C12H13BrN2O2
• Molecular Weight: 297.151
• Mol File: 93299-38-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: L-Tryptophan, 5-bromo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tryptophan, 5-bromo-, methyl ester(93299-38-8)
• EPA Substance Registry System: L-Tryptophan, 5-bromo-, methyl ester(93299-38-8)

Safety Data

• Hazardous Substances Data: 93299-38-8(Hazardous Substances Data)

Upstream product

• 83541-81-5 (S)-dimethyl pyrrolidine-1,2-dicarboxylate 
• 4299-70-1 L-tryptophan methyl ester 
• 66377-68-2 N-(methoxycarbonyl)-L-tryptophan methyl ester 
• 1370458-22-2 dimethyl (2S,3aR,8aS)-8-acetyl-5-bromo-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-1,2-dicarboxylate 
• 1370458-21-1 dimethyl (2S,3aR,8aS)-8-acetyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole-1,2-dicarboxylate 
• 67-56-1 methanol 
• 6548-09-0 5-bromo-DL-tryptophan 
• 74761-41-4 (S)-1-(methoxycarbonyl)pyrrolidine-2-carboxylic acid 
• 147-85-3 L-proline 
• 93299-30-0 N-methoxycarbonyl-L-glutamine methyl ester 
• 93271-96-6 (2S,5RS)-1,2-dimethyl-5-hydroxypyrrolidine-1,2-dicarboxylate 
• 93271-98-8 N-methoxycarbonyl-4-cyano-L-2-aminobutyric acid methyl ester 
• 93272-06-1 5-bromo-N_b-methoxycarbonyl-L-tryptophan methyl ester 
• 67811-39-6 8-Acetyl-3,3a,8,8a-tetrahydro-2H-pyrrolo[2,3-b]indole-1,2-dicarboxylic acid dimethyl ester 

Downstream Products

• 1370458-23-3 Boc-Ise(TBDPS)-Trp(5-Br)-OMe 
• 1370458-05-1 Boc-Ise(TBDPS)-Trp(5-Br)-OH 
• 1370458-06-2 C₅₆H₆₅BrCl₄N₈O₁₃Si 
• 1370458-07-3 C₄₀H₄₇BrCl₄N₈O₁₃ 
• 1370458-17-5 C₄₇H₄₇BrCl₄N₈O₁₀Si 
• 1370458-18-6 C₄₀H₄₇BrCl₄N₈O₁₃ 
• 1370458-08-4 C₅₆H₆₅BrCl₄N₈O₁₃Si 
• 1370458-09-5 C₄₇H₄₇BrCl₄N₈O₁₀Si 
• 6548-09-0 5-bromo-L-tryptophan 

Relevant articles and documents

A One-Pot Synthesis of Symmetrical and Unsymmetrical Dipeptide Ureas

We describe a flexible and high yielding synthesis of 1,3-disubstituted ureas that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C-labelled ureas, from amino acids and carbon dioxide at atmospheric pressure. We describe a flexible and high yielding synthesis of 1,3-disubstituted ureas, that allows for the construction of both symmetrical and unsymmetrical dipeptide ureas, including easy access to 13C labelled ureas, from amino acids and carbon dioxide at atmospheric pressure.

N-benzoyl amino acids as LFA-1/ICAM inhibitors 1: Amino acid structure-activity relationship

The association of ICAM-1 with LFA-1 plays a critical role in several autoimmune diseases. N-2-Bromobenzoyl L-tryptophan, compound 1, was identified as an inhibitor to the formation of the LFA-1/ICAM complex. The SAR of the amino acid indicates that the carboxylic acid is required for inhibition and that L-histidine is the most favored amino acid.