93304-03-1

Basic information

• Product Name: Ethanone, 1-(1-methyl-1H-pyrrol-2-yl)-2-phenyl-
• CAS NO: 93304-03-1
• Molecular Formula: C13H13NO
• Molecular Weight: 199.252
• Mol File: 93304-03-1.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-(1-methyl-1H-pyrrol-2-yl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(1-methyl-1H-pyrrol-2-yl)-2-phenyl-(93304-03-1)
• EPA Substance Registry System: Ethanone, 1-(1-methyl-1H-pyrrol-2-yl)-2-phenyl-(93304-03-1)

Safety Data

• Hazardous Substances Data: 93304-03-1(Hazardous Substances Data)

Upstream product

• 96-54-8 N-Methylpyrrole 
• 103-80-0 phenylacetyl chloride 
• 932-16-1 N-methyl-2-acetylpyrrole 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 
• 34438-71-6 acetophenone enolate 
• 6973-60-0 1-Methyl-2-pyrrolecarboxylic acid 
• 140-29-4 phenylacetonitrile 
• 1085430-85-8 2-(1-methyl-1H-pyrrol-2-yl)-3-phenylpropanamide 
• 117068-07-2 α-(dimethylamino)-α-(1-methylpyrrol-2-yl)acetonitrile 
• 100-39-0 benzyl bromide 
• 26214-68-6 1-methyl-pyrrole-2-carboxylic acid chloride 
• 93303-99-2 <(1-methyl-2-pyrrolyl)carbonyl>trimethylsilane 

Downstream Products

• 1338919-40-6 (2R)-2-(1-methyl-5-(phenylacetyl)-1H-pyrrol-3-yl)-2-hydroxyacetic acid n-butyl ester 
• 126231-23-0 2-bromo-1-(1-methyl-1H-pyrrol-2-yl)-2-phenylethanone 
• 126231-25-2 2-Bromo-1-(5-bromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 126231-27-4 2-Bromo-1-(4-bromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 126231-29-6 2-Bromo-1-(4,5-dibromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 126231-24-1 1-(5-Bromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 126231-26-3 1-(4-Bromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 126231-28-5 1-(4,5-Dibromo-1-methyl-1H-pyrrol-2-yl)-2-phenyl-ethanone 
• 86012-92-2 1-(1-Methyl-1H-pyrrol-2-yl)-2-phenylethanol 

Relevant articles and documents

Acylation of pyrroles and their free (N-H)-derivatives via palladium-catalyzed carbopalladation of nitriles

An efficient regioselective synthesis of 2-acylpyrroles via palladium-catalyzed addition of pyrroles with benzonitriles and subsequent hydrolysis is developed. The direct acylation reaction of protected as well as (NH)-free pyrroles proceeded smoothly to

Oxidative conversion of α,α-disubstituted acetamides to corresponding one-carbon-shorter ketones using hypervalent iodine (λ5) reagents in combination with tetraethylammonium bromide

(Chemical Equation Presented) α,α-Disubstituted acetamides undergo oxidative dehomologation to give one-carbon-shorter ketones when reacted with a hypervalent iodine (λ5) reagent in combination with tetraethylammonium bromide (TEAB) in various solvents. In further studies, one such combination of a hypervalent iodine (λ5) reagent, o-iodoxybenzoic acid, and TEAB has been established as a new, mild, efficient, and general method for the transformation.

Ytterbium (III) trifluoromethanesulfonate catalysed Friedel-Crafts acylation of 1-methylpyrrole in ionic liquid

In the presence of a catalytic amount of ytterbium (III) trifluoromethanesulfonate [Yb(OTf)3], 1-methylpyrrole can easily react with acyl chlorides in an ionic liquid [bpy][BF4](bpy=1- butylpyridine) to form corresponding ketones in satisfactory yield. The recyclability of the ionic liquid/catalyst system is demonstrated.