933460-58-3

Basic information

• Product Name: 1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine
• Synonyms: 1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine
• CAS NO: 933460-58-3
• Molecular Weight: 606.659
• Mol File: 933460-58-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine(933460-58-3)
• EPA Substance Registry System: 1-{(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)]propyl}-5-azacytosine(933460-58-3)

Safety Data

• Hazardous Substances Data: 933460-58-3(Hazardous Substances Data)

Upstream product

• 98432-80-5 diisopropyl (bromomethyl)phosphonate 
• 129940-50-7 (S)-tritylglycidol 
• 933460-54-9 1-[(2S)-2-hydroxy-3-(triphenylmethoxy)propyl]-5-azacytosine 

Downstream Products

• 1608459-53-5 (S,E)-(8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazahentriacont-7-en-1-yl)phosphonic acid 
• 124-26-5 stearamide 
• 1608457-43-7 1-(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)propyl-N⁴-docosanoyl-5-azacytosine] 
• 1608459-54-6 (S,E)-diisopropyl {8-amino-6,10-dioxo-3-[(trityloxy)methyl]-2-oxa-5,7,9-triazaheptacos-7-en-1-yl}phosphonate 
• 1608459-55-7 (S,E)-diisopropyl [8-amino-3-(hydroxymethyl)-6,10-dioxo-2-oxa-5,7,9-triazaheptacos-7-en-1-yl]phosphonate 
• 1608457-44-8 1-(2S)-2-[(diisopropoxyphosphoryl)methoxy-3-(triphenylmethoxy)propyl]-N⁴-octadeca-noyl-5-azacytosine 
• 941293-56-7 C₃₁H₄₁N₄O₆P 

Relevant articles and documents

Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2- (phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds

Treatment of 5-azacytosine sodium salt with diisopropyl [(2-chloroethoxy)methyl]phosphonate followed by removal of ester groups with BrSi(CH3)3 afforded 1-[2-(phosphonomethoxy)ethyl]-5- azacytosine (3). Reaction of 5-azacytosine with