93351-55-4

Basic information

• Product Name: 1,3-Dioxane-4-methanol,2-phenyl-(9CI)
• Synonyms: 1,3-Dioxane-4-methanol,2-phenyl-(9CI)
• CAS NO: 93351-55-4
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.22706
• Product Categories: PHENYL
• Mol File: 93351-55-4.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane-4-methanol,2-phenyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4-methanol,2-phenyl-(9CI)(93351-55-4)
• EPA Substance Registry System: 1,3-Dioxane-4-methanol,2-phenyl-(9CI)(93351-55-4)

Safety Data

• Hazardous Substances Data: 93351-55-4(Hazardous Substances Data)

Usage

General Description

1,3-Dioxane-4-methanol,2-phenyl-(9CI) is a chemical compound also known as 2-phenyl-1,3-dioxane-4-methanol. It is a type of phenyldioxane, which is a class of organic compounds containing a dioxane ring with a phenyl group attached to it. This particular compound is used in the synthesis of pharmaceuticals, fine chemicals, and agricultural products. It is also utilized as a solvent in various industrial applications. However,

Upstream product

• 3068-00-6 D,L-1,2,4-butanetriol 
• 100-52-7 benzaldehyde 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 70005-88-8 (R)-1,2,4-butanetriol 
• 3969-69-5 (+/-)-cis-4-hydroxymethyl-2-phenyl-1,3-dioxolane 

Downstream Products

• 140210-14-6 (R,R)-4-(Acetoxymethyl)-2-phenyl-1,3-dioxane 
• 140210-14-6 (S,S)-4-(Acetoxymethyl)-2-phenyl-1,3-dioxane 
• 102794-92-3 (2R,4R)-4-formyl-2-phenyl-1,3-dioxane 
• 103773-79-1 [(2S,4S)-2-phenyl-1,3-dioxan-4-yl]methanol 
• 3969-69-5 (-)-cis-4-hydroxymethyl-2-phenyl-1,3-dioxolane 
• 1010702-34-7 C₁₂H₁₆O₅S 
• 134665-70-6 (Z)-3-((2R,4R)-2-Phenyl-[1,3]dioxan-4-yl)-acrylic acid methyl ester 
• 602314-28-3 (Z)-3-((2R,4R)-2-Phenyl-[1,3]dioxan-4-yl)-acrylic acid methyl ester 
• 1402820-10-3 C₁₂H₁₂O₂ 

Relevant articles and documents

Total Synthesis and Biological Evaluation of Siladenoserinol A and its Analogues

The total synthesis of siladenoserinol A, an inhibitor of the p53–Hdm2 interaction, has been achieved. AuCl3-catalyzed hydroalkoxylation of an alkynoate derivative smoothly and regioselectively proceeded to afford a bicycloketal in excellent yield. A glycerophosphocholine moiety was successfully introduced through the Horner–Wadsworth–Emmons reaction using an originally developed phosphonoacetate derivative. Finally, removal of the acid-labile protecting groups, followed by regioselective sulfamate formation of the serinol moiety afforded the desired siladenoserinol A, and benzoyl and desulfamated analogues were also successfully synthesized. Biological evaluation showed that the sulfamate is essential for biological activity, and modification of the acyl group on the bicycloketal can improve the inhibitory activity against the p53–Hdm2 interaction.

ANTIBACTERIAL AGENTS

Antibacterial compounds of formula (I) are provided, as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

New and concise approach to (R)-α-lipoic acid

A concise enantiospecific synthesis of (S)-6,8-bis(methylsulfonyloxy)- octanoic acid (2), a ready precursor of (R)-(+)-α-lipoic acid (1), is reported. The key step of the synthesis is the coupling of the tosylate derived from (R)-malic acid with phenylpro