933671-83-1

Basic information

• Product Name: 1-Bromo-2-iodo-3,5-dimethylbenzene
• Synonyms: 1-Bromo-2-iodo-3,5-dimethylbenzene
• CAS NO: 933671-83-1
• Molecular Formula: C₈H₈BrI
• Molecular Weight: 310.95759
• Mol File: 933671-83-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Bromo-2-iodo-3,5-dimethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-iodo-3,5-dimethylbenzene(933671-83-1)
• EPA Substance Registry System: 1-Bromo-2-iodo-3,5-dimethylbenzene(933671-83-1)

Safety Data

• Hazardous Substances Data: 933671-83-1(Hazardous Substances Data)

Usage

Type of compound

Halogenated benzene derivative

Structure

Benzene ring with two methyl groups at the 3 and 5 positions, a bromine atom at the 1 position, and an iodine atom at the 2 position

Uses

Building block in organic synthesis and pharmaceutical manufacturing

Potential applications

Reagent in the synthesis of various biologically active compounds

Safety concerns

Potential toxicity and environmental impact; should be handled and disposed of with care

Upstream product

• 41825-73-4 2-bromo-4,6-dimethylaniline 

Downstream Products

• 4212-74-2 2,4-dimethylphenyl phenyl sulfone 
• 107774-56-1 3,5-dimethyl-1-(phenylsulphonyl)benzene 
• 110348-41-9 3,5-dimethyl-1,2-bis(phenylsulphonyl)benzene 

Relevant articles and documents

Ruthenium-Catalyzed Cycloisomerization of 2,2′-Diethynyl- biphenyls Involving Cleavage of a Carbon-Carbon Triple Bond

A ruthenium complex catalyzes a new cycloisomerization reaction of 2,2′-diethynylbiphenyls to form 9-ethynylphenanthrenes, thereby cleaving the carbon-carbon triple bond of the original ethynyl group. A metal-vinylidene complex is generated from one of th

Palladium-catalyzed aryl amination-heck cyclization cascade: A one-flask approach to 3-substituted indoles

(Chemical Equation Presented) Two for the price of one: A Pd/dppf-based catalyst provides access to the title compounds from 1,2-dihalogenated aromatic compounds and allylic amines in a single reaction flask. The initial aryl amination step occurs with excellent selectivity for the aryl iodide to ensure the formation of a single indole regioisomer, which can be functionalized in situ by N-arylation (see scheme). dba = dibenzylideneacetone, dppf = 1,1′-bis(diphenylphospanyl)ferrocene.