933687-81-1Relevant articles and documents
Synthesis and conformational properties of N-monoalkyl 1,5-diaza-cis-decalins
Xie, Xu,Freed, Dana A.,Kozlowski, Marisa C.
, p. 6451 - 6454 (2007/10/03)
N-Monoalkyl 1,5-diaza-cis-decalins were synthesized in high yield and purity by derivatization of tetrahydronaphthyridine followed by reduction to the saturated system. The position of the conformational equilibrium between the chair-chair inversion forms of a series of four N-monoalkyl of 1,5-diaza-cis-decalins was measured and was directly related to the size of the N-alkyl group.