93397-22-9Relevant articles and documents
Influence of the dipeptide linker configuration on the activity of PSMA ligands
Uspenskaya, Anastasiya A.,Machulkin, Alexey E.,Nimenko, Ekaterina A.,Shafikov, Radik R.,Petrov, Stanislav A.,Skvortsov, Dmitry A.,Beloglazkina, Elena K.,Majouga, Alexander G.
, p. 756 - 759 (2021/01/12)
Selective ligands of an urea-based prostate specific membrane antigen with a phenylalanine/tyrosine-based dipeptide linker and with a mingled chiral centers configuration and/or substituted aromatic fragments were prepared in seven steps by liquid- and in
On the Role of Chirality in Guiding the Self-Assembly of Peptides
Basak, Shibaji,Singh, Ishwar,Ferranco, Annaleizle,Syed, Jebreil,Kraatz, Heinz-Bernhard
, p. 13288 - 13292 (2017/10/07)
Homochirality in peptides is crucial in sustaining “like–like” intermolecular interactions that allow the formation of assemblies and aggregates and is ultimately responsible for the resulting material properties. With the help of a series of stereoisomer
Epimerization-free C-terminal peptide activation
Popovic, Stanimir,Bieraeugel, Hans,Detz, Remko J.,Kluwer, Alexander M.,Koole, Jelmer A. A.,Streefkerk, Dieuwertje E.,Hiemstra, Henk,Van Maarseveen, Jan H.
supporting information, p. 16934 - 16937 (2014/01/06)
Smooth operation: C-terminal peptide activation with full stereointegrity was accomplished using a copper(II)-mediated coupling reaction of carboxylic acids with arylboroxines (see scheme, NCL = native chemical ligation, Boc = tert-butoxycarbonyl). This method allows epimerization-free activation and ligation of peptides with racemization-prone phenylglycine at the C terminus.
