934008-41-0

Basic information

• Product Name: (Z)-(7R,8S)-8-methyl-7-((R)-2-methyl-propane-2-sulfinylamino)-non-4-enedioc acid 9-(4-methoxy-benzyl) ester 1-(2,2,2-trichloro-ethyl) ester
• Synonyms: (Z)-(7R,8S)-8-methyl-7-((R)-2-methyl-propane-2-sulfinylamino)-non-4-enedioc acid 9-(4-methoxy-benzyl) ester 1-(2,2,2-trichloro-ethyl) ester
• CAS NO: 934008-41-0
• Molecular Weight: 570.962
• Mol File: 934008-41-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-(7R,8S)-8-methyl-7-((R)-2-methyl-propane-2-sulfinylamino)-non-4-enedioc acid 9-(4-methoxy-benzyl) ester 1-(2,2,2-trichloro-ethyl) ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(7R,8S)-8-methyl-7-((R)-2-methyl-propane-2-sulfinylamino)-non-4-enedioc acid 9-(4-methoxy-benzyl) ester 1-(2,2,2-trichloro-ethyl) ester(934008-41-0)
• EPA Substance Registry System: (Z)-(7R,8S)-8-methyl-7-((R)-2-methyl-propane-2-sulfinylamino)-non-4-enedioc acid 9-(4-methoxy-benzyl) ester 1-(2,2,2-trichloro-ethyl) ester(934008-41-0)

Safety Data

• Hazardous Substances Data: 934008-41-0(Hazardous Substances Data)

Upstream product

• 6089-09-4 4-pentynoic acid 
• 934008-37-4 7,8-dihydroxy-oct-4-ynoic acid 2,2,2-trichloro-ethyl ester 
• 934008-38-5 (Z)-7,8-dihydroxy-oct-4-enoic acid 2,2,2-trichloro-ethyl ester 
• 934008-36-3 oct-7-en-4-ynoic acid 2,2,2-trichloro-ethyl ester 
• 934008-39-6 (Z)-7-oxo-hept-4-enoic acid 2,2,2-trichloro-ethyl ester 
• 913055-64-8 4-pentynoic acid 2,2,2-trichloro-ethyl ester 
• 934008-40-9 (Z)-7-[(E)-(R)-2-methyl-propane-2-sulfinylimino]-hept-4-enoic acid 2,2,2-trichloro-ethyl ester 
• 7549-33-9 (4-methoxyphenyl)methyl propanoate 

Relevant articles and documents

Total synthesis of azumamide A and azumamide E, evaluation as histone deacetylase inhibitors, and design of a more potent analogue

(Chemical Equation Presented) The unprecedented diastereoselective Mannich reaction of a Z-allylsulfoximine was a key step in the total synthesis of the marine natural products azumamide A and E, and an unnatural analogue. Their relative potency as histone deacetylase inhibitors was evaluated and found to correlate with predicted zinc-binding affinity.