93436-35-2Relevant articles and documents
Nickel-catalyzed reductive cyclization of alkyl dihalides
Xue, Weichao,Xu, Hailiang,Liang, Zhuye,Qian, Qun,Gong, Hegui
supporting information, p. 4984 - 4987 (2014/12/11)
The reductive coupling protocol to intramolecular cyclization of dihaloalkanes is presented. It leads to five- and six-membered rings, with the former being more efficient. The incorporation of secondary alkyl halides generally promotes coupling efficiency. To the best of our knowledge, this is the first catalytic ring-closure reaction arising from dihaloalkanes under chemical reductive conditions.