934371-48-9 Usage
Description
(+)-(L)-2-(N'-cyclohexylidenehydrazino)-3-(3,4-dihydroxyphenyl)-2-methyl propionic acid methyl ester is a complex organic compound with a unique molecular structure. It is characterized by the presence of a cyclohexylidenehydrazino group, a dihydroxyphenyl moiety, and a methyl ester functional group. (+)-(L)-2-(N'-cyclohexylidenehydrazino)-3-(3,4-dihydroxyphenyl)-2-methyl propionic acid methyl ester exhibits chiral properties, with the (+)-(L) configuration indicating its specific spatial arrangement.
Uses
Used in Pharmaceutical Industry:
(+)-(L)-2-(N'-cyclohexylidenehydrazino)-3-(3,4-dihydroxyphenyl)-2-methyl propionic acid methyl ester is used as an impurity in the synthesis of Carbidopa, a prodrug inhibitor of aromatic amino acid decarboxylase. Its presence in the synthesis process is crucial for the development and production of Carbidopa, which is an essential component in the treatment of Parkinson's disease and other movement disorders.
In the pharmaceutical industry, the compound plays a significant role in the synthesis of Carbidopa, which is a crucial drug for managing the symptoms of Parkinson's disease. As an impurity, it contributes to the overall effectiveness and potency of the final drug product. (+)-(L)-2-(N'-cyclohexylidenehydrazino)-3-(3,4-dihydroxyphenyl)-2-methyl propionic acid methyl ester's unique structure and properties make it a valuable component in the development of innovative pharmaceuticals and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 934371-48-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,4,3,7 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 934371-48:
(8*9)+(7*3)+(6*4)+(5*3)+(4*7)+(3*1)+(2*4)+(1*8)=179
179 % 10 = 9
So 934371-48-9 is a valid CAS Registry Number.
934371-48-9Relevant articles and documents
PROCESS FOR THE PREPARATION OF CARBIDOPA
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Page/Page column 20, (2008/06/13)
The invention relates to a process for the preparation of (-) - (L) -3- (3,4-dihydroxyphenyl) -2-hydrazino-2 -methyl propionic acid (carbidopa) of the formula (II) by using 3, 3 -pentamethylene oxaziridine of the formula (IV), which comprises reacting L-α-methyldopa methyl ester of the formula (III) with 3,3-penta- methylene oxaziridine of the formula (IV), isolating the thus-obtained (+) - (L) -2- (N' - cyclohexylidene-hydrazino) -3- (3 , 4-dihydroxy phenyl) -2 -methyl propionic acid methyl ester of the formula (I) (I) and subjecting it to hydrolysis with an acid. (+) - (L) -2- (N' -cyclohexylidene-hydrazino) -3-(3,4-dihydroxyphenyl) -2-methyl propionic acid methyl ester of the formula (I) is a new intermediate . (-) - (L)-3-(3,4-dihydroxyphenyl) -2-hydrazino-2- methyl propionic acid (carbidopa) of the formula (XI) thus obtained is a valuable therapeutic active ingredient having the international non-proprietary name carbidopa.
