93483-71-7

Basic information

• Product Name: 4-AMINO-N-(TERT-BUTYL)BENZAMIDE
• Synonyms: 4-AMINO-N-(TERT-BUTYL)BENZAMIDE;N-tert-butyl-4-aminobenzamide
• CAS NO: 93483-71-7
• Molecular Formula: C₁₁H₁₆N₂O
• Molecular Weight: 192.25754
• Mol File: 93483-71-7.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 372.3±25.0 °C(Predicted)
• Appearance: /
• Density: 1.058±0.06 g/cm3(Predicted)
• PKA: 15.83±0.46(Predicted)
• CAS DataBase Reference: 4-AMINO-N-(TERT-BUTYL)BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-N-(TERT-BUTYL)BENZAMIDE(93483-71-7)
• EPA Substance Registry System: 4-AMINO-N-(TERT-BUTYL)BENZAMIDE(93483-71-7)

Safety Data

• Hazardous Substances Data: 93483-71-7(Hazardous Substances Data)

Usage

General Description

4-AMINO-N-(TERT-BUTYL)BENZAMIDE is a chemical compound that consists of a benzene ring with an attached amino group, an amide group, and a tert-butyl group. It is used as a building block in organic synthesis and can be utilized to create various pharmaceuticals, agrochemicals, and materials. 4-AMINO-N-(TERT-BUTYL)BENZAMIDE has the potential to exhibit various biological activities and can act as an inhibitor or activator of certain enzymes or receptors. Additionally, it has been studied for its potential antimicrobial and anticancer properties. The tert-butyl group provides steric hindrance, which can impact the compound's reactivity and biological interactions. Overall, 4-AMINO-N-(TERT-BUTYL)BENZAMIDE is a versatile chemical with diverse potential applications in the fields of medicine, agriculture, and materials science.

Upstream product

• 42498-30-6 N-tert-butyl-4-nitrobenzamide 
• 122-04-3 4-nitro-benzoyl chloride 
• 98-88-4 benzoyl chloride 
• 75-64-9 tert-butylamine 
• 540-88-5 acetic acid tert-butyl ester 
• 873-74-5 4-Aminobenzonitrile 
• 62-23-7 4-nitro-benzoic acid 
• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 

Downstream Products

• 95005-17-7 2-(4-tert.-Butylcarbamoyl-phenylcarbamoyl)-2-(4-chlor-phenoxy)-propan 
• 205492-91-7 4-[(4,6-dichloro-1,3,5-triazine-2-yl)amino]-N-(1,1-dimethylethyl)benzamide 
• 608523-51-9 6-[4-(tert-Butylcarbamoyl)phenylazo]-pyridoxal-5-phosphate 
• 1417547-04-6 N-(4-(tert-butylcarbamoyl)phenylcarbamoyl)-2,6-difluorobenzamide 

Relevant articles and documents

VASCULAR ADHESION PROTEIN-1 (VAP-1) MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule Vascular Adhesion Protein- 1 (VAP-1) modulator compositions, pharmaceutical compositions, the use and preparation thereof.

Synthesis and antitumor activity of novel phenylhydrazonopyrazolone derivatives and molecular dynamics simulations

SHP2 is a new promising target for anti-cancer drug discovery. A series of novel phenylhydrazonopyrazolone derivatives was synthesized by a more convenient method, and their chemical structures were characterized by various spectroscopic methods. The inhibitory effects of these compounds on SHP2 enzyme and SHP2-dependent cancer cell H1975 were evaluated. The compound 11f with IC50 value of 3.38?μmol/L exhibited more potent antitumor activity against H1975 cell than GS-493 (IC50 = 20.92?μmol/L). Molecular dynamics simulation of compound 11f displayed a possible mode of interaction between this compound and SHP2 enzyme.

Design, synthesis, and insecticidal evaluation of new benzoylureas containing amide and sulfonate groups based on the sulfonylurea receptor protein binding site for diflubenzuron and glibenclamide

On the basis of the sulfonylurea receptor (SUR) protein binding site for diflubenzuron and glibenclamide, 15 new benzoylphenylureas containing amide and sulfonate groups were designed and synthesized. Their structures were characterized by 1H n