934995-58-1

Basic information

• Product Name: Dispyrin
• Synonyms: Dispyrin
• CAS NO: 934995-58-1
• Molecular Weight: 473.208
• Mol File: 934995-58-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Dispyrin(CAS DataBase Reference)
• NIST Chemistry Reference: Dispyrin(934995-58-1)
• EPA Substance Registry System: Dispyrin(934995-58-1)

Safety Data

• Hazardous Substances Data: 934995-58-1(Hazardous Substances Data)

Upstream product

• 72652-32-5 1-(4-bromo-1H-pyrrol-2-yl)-2,2,2-trichloroethanone 
• 1093249-39-8 C₁₃H₂₁BrN₂O 
• 27746-02-7 4-bromo-1H-pyrrole-2-carboxylic acid 
• 159465-27-7 3-Bromo-4-methoxyphenethylamine 
• 1069472-63-4 4-bromo-N-(3-bromo-4-methoxyphenethyl)-1H-pyrrole-2-carboxamide 
• 1069472-64-5 4-bromo-N-(3-bromo-4-hydroxyphenethyl)-1H-pyrrole-2-carboxamide 
• 109-54-6 3-(Dimethylamino)propyl chloride 

Downstream Products

• 1069472-65-6 4-bromo-N-(3-bromo-4-(3-(dimethylamino)propoxy)phenethyl)-1H-pyrrole-2-carboxamide hydrochloride 
• 1093249-43-4 dispyrin trifluoroacetate 

Relevant articles and documents

UNNATURAL DISPYRIN ANALOGUES, PREPARATION AND USES THEREOF

Disclosed are dispyrin analogue compounds useful as H3 receptor activity modulators, methods of making same, pharmaceutical compositions comprising same, and methods of treating neurological and psychiatric disorders associated with histamine H3 receptor activity using same. In one aspect, the disclosed analogues can have a structure represented by a formula: (I), This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Total synthesis of dispyrin, purpurealidin E, and aplysamine-1

Bromotyrosine alkaloids dispyrin (1), purpurealidin E (2), and aplysamine-1 (3) isolated from marine sponge, were synthesized from commercially available tyramine (4) as a common starting material. The overall yield was 18%, 39%, and 22% for 1 from 4 in 5