93549-15-6

Basic information

• Product Name: 3,4-Dihydro-6-methoxyisoquinoline hydrochloride
• Synonyms: 3,4-Dihydro-6-methoxyisoquinoline hydrochloride;3,4-Dihydro-6-methoxyisoquinoline;6-Methoxy-3,4-dihydroisoquinoline hydrochloride;Isoquinoline,3,4-dihydro-6-methoxy-,hydrochloride
• CAS NO: 93549-15-6
• Molecular Formula: C10H12ClNO
• Molecular Weight: 197.66
• Product Categories: API intermediates
• Mol File: 93549-15-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 324.9 °C at 760 mmHg
• Flash Point: 150.3 °C
• Appearance: /
• Vapor Pressure: 0.000174mmHg at 25°C
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 3,4-Dihydro-6-methoxyisoquinoline hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-6-methoxyisoquinoline hydrochloride(93549-15-6)
• EPA Substance Registry System: 3,4-Dihydro-6-methoxyisoquinoline hydrochloride(93549-15-6)

Safety Data

• Hazardous Substances Data: 93549-15-6(Hazardous Substances Data)

Usage

Description

3,4-Dihydro-6-methoxyisoquinoline hydrochloride is an organic compound that serves as a crucial reagent in the synthesis of various pharmaceutical agents. It is characterized by its unique chemical structure, which includes a dihydroisoquinoline core with a methoxy group at the 6th position and a hydrochloride counterion. 3,4-Dihydro-6-methoxyisoquinoline hydrochloride plays a significant role in the development of adrenergic antagonists, which are essential in the treatment of various medical conditions.

Uses

Used in Pharmaceutical Industry:
3,4-Dihydro-6-methoxyisoquinoline hydrochloride is used as a key intermediate in the synthesis of 2-(aminobenzyl)-1,2,3,4-tetrahydroisoquinolines. These compounds exhibit adrenergic antagonist properties, which are crucial in the development of medications targeting the adrenergic system. Adrenergic antagonists are used to treat a wide range of conditions, including hypertension, heart diseases, and asthma, by blocking the action of catecholamines on adrenergic receptors.
In the synthesis process, 3,4-Dihydro-6-methoxyisoquinoline hydrochloride acts as a precursor, undergoing chemical reactions to form the desired adrenergic antagonists. Its unique structure allows for the introduction of various functional groups, enabling the creation of a diverse range of pharmaceutical agents with different therapeutic properties.
Furthermore, 3,4-Dihydro-6-methoxyisoquinoline hydrochloride may also be utilized in the research and development of new drugs targeting the adrenergic system. Its role as a reagent allows scientists to explore the structure-activity relationships of adrenergic antagonists, leading to the discovery of more potent and selective compounds with improved therapeutic profiles.

InChI:InChI=1/C10H11NO.ClH/c1-12-10-3-2-9-7-11-5-4-8(9)6-10;/h2-3,6-7H,4-5H2,1H3;1H