936-03-8Relevant articles and documents
Efficient and Practical Arene Hydrogenation by Heterogeneous Catalysts under Mild Conditions
Maegawa, Tomohiro,Akashi, Akira,Yaguchi, Kiichiro,Iwasaki, Yohei,Shigetsura, Masahiro,Monguchi, Yasunari,Sajiki, Hironao
experimental part, p. 6953 - 6963 (2010/02/28)
An efficient and practical arene hydrogenation procedure based on the use of heterogeneous platinum group catalysts has been developed. Rh/C is the most effective catalyst for the hydrogenation of the aromatic ring, which can be conducted in iPrOH under neutral conditions and at ordinary to medium H 2 pressures (10 atm). A variety of arenes such as alkylbenzenes, benzoic acids, pyridines, furans, are hydrogenated to the corresponding cyclohexyl and heterocyclic compounds in good to excellet yields. The use of Ru/C, less expensive than Rh/C, affords an effective and practical method for the hydrogenation of arenes including phenols. Both catalysts can be reused several times after simple filtration without any significant loss of catalytic activity.
Efficient cyclization of ω-oxo-α,β-unsaturated esters using lithium thiolate-initiated Michael-aldol tandem reaction
Ono, Masashi,Nishimura, Katsumi,Nagaoka, Yasuo,Tomioka, Kiyoshi
, p. 6979 - 6982 (2007/10/03)
The reaction of ω-oxo-α,β-unsaturated esters with lithium thiolates afforded the Michael-aldol tandem cyclization products in good to perfect stereoselectivity depending on the nature of thiolates.
Phosphorylated Sugars. Part 23. Synthesis and Reactions of Phosphodiesters containing 2-Aminoethanol and a Polyfunctional Alcohol and their Behaviour during Acid- and Base-catalysed Hydrolysis
Trigalo, Francois,Szabo, Ladislas
, p. 1733 - 1744 (2007/10/02)
Phosphodiesters of 2-aminoethanol and of polyhydroxylated alcohols and sugars have been synthesised; their behaviour in M-HCl and in saturated (ca. 0.2 M) Ba(OH)2 solutions at 100 deg C have been examined.With the exception of 2-aminoethyl ethyl phosphate which, in acidic medium, yielded 2-aminoethylphosphate, free 2-aminoethanol and phosphorylated polyols or sugars were the main products formed.Because of simultaneously and/or sequentially occurring reactions the structures of the phosphorylated derivatives formed gave no unambiguous information regarding the structure of the initial phosphodiester.
