936-47-0

Basic information

• Product Name: 5-phenyl-4,5-dihydro-1H-pyrazole
• Synonyms: 1H-pyrazole, 4,5-dihydro-5-phenyl-; 5-Phenyl-4,5-dihydro-1H-pyrazole
• CAS NO: 936-47-0
• Molecular Formula: C₉H₁₀N₂
• Molecular Weight: 146.1891
• Mol File: 936-47-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 287.7°C at 760 mmHg
• Flash Point: 127.8°C
• Density: 1.12g/cm³
• Vapor Pressure: 0.00424mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: 5-phenyl-4,5-dihydro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-phenyl-4,5-dihydro-1H-pyrazole(936-47-0)
• EPA Substance Registry System: 5-phenyl-4,5-dihydro-1H-pyrazole(936-47-0)

Safety Data

• Hazardous Substances Data: 936-47-0(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 

Downstream Products

• 5920-40-1 1-(2,4-dinitro-phenyl)-3-phenyl-4,5-dihydro-1H-pyrazole 
• 4888-74-8 1-phenyl-1,3-propanediamine 
• 2458-26-6 3-phenylpyrazole 
• 5581-84-0 3-amino-3-phenylpropanenitrile 
• 140867-96-5 1-tert-butoxycarbonyl-4,5-dihydro-5-phenylpyrazole 
• 142634-65-9 (3R,5R)-3,5-Diphenyl-pyrazolidine 
• 14371-10-9 (E)-3-phenylpropenal 
• 65480-73-1 1-Phenyl-3-benzylidenhydrazono-propen-⁽¹⁾ 
• 873-49-4 cyclopropylbenzene 
• 19293-52-8 racemic 1,3-diphenyl-1,3-propanediamine 
• 135614-40-3 (1R,3R)-1,3-Diphenyl-N,N'-bis-[1-phenyl-meth-(E)-ylidene]-propane-1,3-diamine 
• 135613-89-7 (1R^*,3R^*)-N,N'-dibenzyl-1,3-diphenyl-1,3-propanediamine 
• 140868-00-4 (1R^*,3R^*)-N,N'-dimethyl-1,3-diphenyl-1,3-propanediamine 
• 126568-44-3 3-(N-tert-butoxycarbonylamino)-3-phenylpropanitrile 

Relevant articles and documents

BISHETEROCYCLIC CARBONYL SUBSTITUTED DIHYDROPYRAZOLE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF

Provided are a substituted dihydropyrazole compound as shown in formula I, which compound has a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, wherein the definition of each group in the formula is detailed in the description. In addition, also disclosed are a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating RIPK1-related diseases or conditions.

N-(3-(IMIDAZO[1,2-B]PYRIDAZIN-3-YLETHYNYL)-4-METHYLPHENYL)-5-PHENYL-4,5-DIHYDRO-1H-PYRAZOLE-1-CARBOXAMIDE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR TREATING KINASE-RELATED DISEASES

The N-(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl)-5-phenyl-4,5-dihydro-1H-pyrazole-1-carboxamide derivative exhibits excellent inhibitory activity against at least one kinase selected from the group consisting of ABL1, ABL2, AURKB, BRK, CDK11

HETEROCYCLIC AMIDES AS KINASE INHIBITORS

Disclosed are compounds having the formula: wherein R1 and R2 are as defined herein, and methods of making and using the same.