936074-51-0 Usage
General Description
1-(5-Chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylic acid is a chemical compound with a complex structure consisting of a piperidine ring linked to a benzo[d]oxazole group with a chloro substituent at the 5th position. It also contains a carboxylic acid functional group attached to the piperidine ring. 1-(5-Chlorobenzo[d]oxazol-2-yl)piperidine-4-carboxylic acid has potential applications in medicinal chemistry as it may exhibit pharmacological properties due to its structural features. It may be used in the synthesis of novel pharmaceutical agents or as a research tool in drug discovery and development. Additionally, it is important for researchers to further study its properties, potential uses, and safety considerations before any practical applications are pursued.
Check Digit Verification of cas no
The CAS Registry Mumber 936074-51-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,6,0,7 and 4 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 936074-51:
(8*9)+(7*3)+(6*6)+(5*0)+(4*7)+(3*4)+(2*5)+(1*1)=180
180 % 10 = 0
So 936074-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H13ClN2O3/c14-9-1-2-11-10(7-9)15-13(19-11)16-5-3-8(4-6-16)12(17)18/h1-2,7-8H,3-6H2,(H,17,18)
936074-51-0Relevant articles and documents
Novel benzoxazole inhibitors of mPGES-1
Kablaoui, Natasha,Patel, Snahel,Shao, Jay,Demian, Douglas,Hoffmaster, Keith,Berlioz, Francioise,Vazquez, Michael L.,Moore, William M.,Nugent, Richard A.
, p. 907 - 911 (2013/02/25)
A novel series of potent benzoxazole mPGES-1 inhibitors has been derived from a hit from a high throughput screen. Compound 37 displays mPGES-1 inhibition in an enzyme assay (0.018 μM) and PGE-2 inhibition in a cell-based assay (0.034 μM). It demonstrates 500- and 2500-fold selectivity for mPGES-1 over COX-2 and 6-keto PGF-1α, respectively. In vivo PK studies in dogs demonstrate 55% oral bioavailability and an 7 h half-life.