936251-01-3 Usage
Description
[(trans)-1-benzyl-4-(2,4,5-trifluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester is a carbamic acid ester compound characterized by a pyrrolidine ring with a benzyl and trifluorophenyl substituent, along with a carbamic acid tert-butyl ester group. This chemical structure endows it with potential applications in the field of medicinal chemistry, particularly for the development of pharmaceutical agents targeting neurological and psychiatric disorders.
Uses
Used in Pharmaceutical Industry:
[(trans)-1-benzyl-4-(2,4,5-trifluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester is used as a key intermediate in the synthesis of potential pharmaceutical agents for the treatment of neurological and psychiatric disorders. Its unique chemical structure and pharmacological properties make it a promising candidate for further research and development in the field of medicinal chemistry.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry research, [(trans)-1-benzyl-4-(2,4,5-trifluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester serves as a valuable compound for exploring new drug targets and mechanisms of action. Its specific structural features allow for the investigation of its interactions with various biological targets, potentially leading to the discovery of novel therapeutic approaches for neurological and psychiatric conditions.
Used in Drug Design and Synthesis:
[(trans)-1-benzyl-4-(2,4,5-trifluorophenyl)pyrrolidin-3-yl]carbamic acid tert-butyl ester is utilized as a building block in the design and synthesis of new pharmaceutical agents. Its incorporation into drug candidates can potentially enhance their efficacy, selectivity, and pharmacokinetic properties, making it an important tool in the development of innovative treatments for neurological and psychiatric disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 936251-01-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,6,2,5 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 936251-01:
(8*9)+(7*3)+(6*6)+(5*2)+(4*5)+(3*1)+(2*0)+(1*1)=163
163 % 10 = 3
So 936251-01-3 is a valid CAS Registry Number.
936251-01-3Relevant articles and documents
1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS
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Page/Page column 84, (2013/03/26)
Therapeutic compounds are disclosed having the general formula (I) that are useful for the treatment of metabolic disorders, including type II diabetes. The compounds have activity as agonists of GPR1 19. Compounds having stereochemistry of formula (la) may also demonstrate DPP-IV inhibitory activity.
COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS
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Page/Page column 35, (2010/10/03)
The present invention is directed to therapeutic compounds which have activity as agonists of GPR119 and are useful for the treatment of metabolic disorders including type II diabetes.
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit
Backes, Bradley J.,Longenecker, Kenton,Hamilton, Gregory L.,Stewart, Kent,Lai, Chunqiu,Kopecka, Hana,von Geldern, Thomas W.,Madar, David J.,Pei, Zhonghua,Lubben, Thomas H.,Zinker, Bradley A.,Tian, Zhenping,Ballaron, Stephen J.,Stashko, Michael A.,Mika, Amanda K.,Beno, David W.A.,Kempf-Grote, Anita J.,Black-Schaefer, Candace,Sham, Hing L.,Trevillyan, James M.
, p. 2005 - 2012 (2008/02/01)
A novel series of pyrrolidine-constrained phenethylamines were developed as dipeptidyl peptidase IV (DPP4) inhibitors for the treatment of type 2 diabetes. The cyclohexene ring of lead-like screening hit 5 was replaced with a pyrrolidine to enable paralle
