93634-54-9

Basic information

• Product Name: (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One
• Synonyms: (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One;(4Z)-2-Methyl-4-[(4-methylphenyl)methylene]-5(4H)-oxazolone;(4Z)-2-methyl-4-[(4-methylphenyl)methylidene]-1,3-oxazol-5-one
• CAS NO: 93634-54-9
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.22124
• Mol File: 93634-54-9.mol
• Article Data: 17

Chemical Properties

• Melting Point: 139-140℃
• Boiling Point: 310.7±52.0 °C(Predicted)
• Appearance: /
• Density: 1.14±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.93±0.20(Predicted)
• CAS DataBase Reference: (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One(93634-54-9)
• EPA Substance Registry System: (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One(93634-54-9)

Safety Data

• Hazardous Substances Data: 93634-54-9(Hazardous Substances Data)

Usage

General Description

"(Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One" is a chemical compound with the molecular formula C16H13NO2. It is an oxazolone derivative, and its structure consists of a five-membered oxazole ring with a ketone and an aryl group attached to it. (Z)-2-Methyl-4-(4-Methylbenzylidene)Oxazol-5(4H)-One may have potential applications in pharmaceutical research due to its structural features and potential biological activities. Further research is needed to fully understand its properties and potential uses in various fields.

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 543-24-8 N-acetylglycine 
• 1906-82-7 ethyl acetamidoacetate 

Downstream Products

• 6955-13-1 N-acetyl-4-methyl-phenylalanine 
• 105962-54-7 Z-2-methyl-4-(α-p-methylphenylethylidene)-5(4H)-oxazolone 
• 110841-88-8 N-benzyl-3-p-methylbenzyl-2(1H)-quinoxalinone 
• 5805-83-4 1-benzyl-2-methylbenzimidazole 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 110841-84-4 3-(4-methylbenzyl)quinoxaline-2(1H)-one 
• 110841-93-5 N-phenyl-3-p-methylbenzyl-2(1H)-quinoxalinone 
• 1484-39-5 2-methyl-1-phenyl-1H-benzimidazole 
• 93634-59-4 (Z)-2-acetamido-3-(4-methylphenyl)-2-propenoic acid 
• 37859-31-7 2-(4-methylbenzyl)benzo[d]thiazole 
• 129169-71-7 (4R,5S)-4-Acetylamino-1,3-diphenyl-5-p-tolyl-4,5-dihydro-1H-pyrazole-4-carboxylic acid 
• 5157-10-8 2-methyl-1H-perimidine 
• 102245-00-1 (Z)-methyl 2-acetamido-3-(p-tolyl)acrylate 
• 272770-58-8 4-(diisopropylphosphanyl-p-tolyl-methyl)-2-methyl-5-trimethylsilanyloxy-oxazole 

Relevant articles and documents

Synthesis, biological evaluation and structure-activity relationships of 5-arylidene tetramic acids with antibacterial activity against methicillin-resistant Staphylococcus aureus

The steady rise of the antimicrobial resistance is a major global threat to human health that requires the urgent need for novel antibiotics. In this work we report the synthesis of a small library of 3-subsituted-5-arylidene tetramic acids in order to in

Synthesis of Indole-2-carboxylate Derivatives via Palladium-Catalyzed Aerobic Amination of Aryl C-H Bonds

A direct oxidative C-H amination affording 1-acetyl indolecarboxylates starting from 2-acetamido-3-arylacrylates has been achieved. Indole-2-carboxylates can be targeted with a straightforward deacetylation of the initial reaction products. The C-H amination reaction is carried out using a catalytic Pd(II) source with oxygen as the terminal oxidant. The scope and application of this chemistry is demonstrated with good to high yields for numerous electron-rich and electron-poor substrates. Further reaction of selected products via Suzuki arylation and deacetylation provides access to highly functionalized indole structures.

Benzylidene-oxazolones as photoswitches: Photochemistry and theoretical calculations

The photophysics and photochemistry of a family of compounds proposed as efficient molecular photoswitches is presented. The effect of different light sources, substituents and solvents in the photostationary state has been explored. A detailed mechanisti