936499-93-3

Basic information

• Product Name: (S)-3-PHENYL-BETA-ALANINOL HCL
• Synonyms: (S)-3-PHENYL-BETA-ALANINOL HCL ;(S)-3-Amino-3-phenyl-propan-1-ol hydrochloride;(gammaS)-gamma-Aminobenzenepropanol hydrochloride (1:1);(S)-3-Amino-3-phenyl-1-propanol hydrochloride
• CAS NO: 936499-93-3
• Molecular Formula: C₉H₁₃NO*ClH
• Molecular Weight: 187.66656
• Mol File: 936499-93-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-3-PHENYL-BETA-ALANINOL HCL(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-PHENYL-BETA-ALANINOL HCL(936499-93-3)
• EPA Substance Registry System: (S)-3-PHENYL-BETA-ALANINOL HCL(936499-93-3)

Safety Data

• Hazardous Substances Data: 936499-93-3(Hazardous Substances Data)

Usage

General Description

"(S)-3-Phenyl-beta-alaninol HCl" is a chemical compound that is composed of a beta-alanine molecule with a phenyl group attached to the third carbon atom in the chain. It is commonly used in the production of pharmaceuticals and organic synthesis due to its chiral nature. The compound is often found in the form of a hydrochloride salt, which allows for easier handling and storage. It has been studied for its potential use in the treatment of various medical conditions, and its properties make it a valuable building block for the synthesis of other complex organic molecules.

Upstream product

• 881853-41-4 3-[N-(phenylacetyl)amino]-3-phenyl-1-propanol 
• 406468-05-1 3-[N-(phenylacetyl)amino]-3-phenyl-1-propanol 
• 5650-41-9 3-hydroxy-1-phenylpropan-1-one 
• 6296-54-4 ethyl 2,4-dioxo-4-phenylbutyrate 
• 14593-04-5 3-amino-3-phenyl-1-propanol 

Downstream Products

• 1143535-90-3 (S)-tert-butyl 4-(3-hydroxy-1-phenylpropylcarbamoyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-ylcarbamate 
• 1015248-99-3 (S)-3-(2-benzothiazolylamino)-3-phenylpropan-1-ol 
• 1015248-96-0 2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine 
• 1397712-25-2 (S)-3-(6,6-dimethyl-4,4-dioxo-5-phenyl-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino)-3-phenylpropan-1-ol 
• 1397712-27-4 (S)-3-[5-(4-benzyloxyphenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 
• 1397712-28-5 4-[2-((S)-3-hydroxy-1-phenyl-propylamino)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-5-yl]phenol 
• 1397712-29-6 (S)-3-[5-(4-methoxyphenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 
• 1397712-35-4 (S)-3-(5-biphenyl-4-yl-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino)-3-phenylpropan-1-ol 
• 1397712-34-3 (S)-3-(6,6-dimethyl-4,4-dioxo-5-p-tolyl-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino)-3-phenylpropan-1-ol 
• 1397712-38-7 (S)-3-[5-(2-chlorophenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 
• 1397712-39-8 (S)-3-(6,6-dimethyl-4,4-dioxo-5-o-tolyl-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino)-3-phenylpropan-1-ol 
• 1397712-47-8 (S)-3-[5-(3-benzyloxyphenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 
• 1397712-60-5 (S)-3-[5-(3-methoxyphenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 
• 1397712-43-4 (S)-3-[5-(3-chlorophenyl)-6,6-dimethyl-4,4-dioxo-5,6-dihydro-4H-4lambda6-[1,4,3]-oxathiazin-2-ylamino]-3-phenylpropan-1-ol 

Relevant articles and documents

A Practical Electrophilic Nitrogen Source for the Synthesis of Chiral Primary Amines by Copper-Catalyzed Hydroamination

A mild and practical method for the catalytic installation of the amino group across alkenes and alkynes has long been recognized as a significant challenge in synthetic chemistry. As the direct hydroamination of olefins using ammonia requires harsh conditions, the development of suitable electrophilic aminating reagents for formal hydroamination methods is of importance. Herein, we describe the use of 1,2-benzisoxazole as a practical electrophilic primary amine source. Using this heterocycle as a new amino group delivery agent, a mild and general protocol for the copper-hydride-catalyzed hydroamination of alkenes and alkynes to form primary amines was developed. This method provides access to a broad range of chiral α-branched primary amines and linear primary amines, as demonstrated by the efficient synthesis of the antiretroviral drug maraviroc and the formal synthesis of several other pharmaceutical agents.