936724-58-2

Basic information

• Product Name: (E)-tert-butyl((3,3-dimethylhepta-4,6-dien-1-yl)oxy)diphenylsilane
• Synonyms: (E)-tert-butyl((3,3-dimethylhepta-4,6-dien-1-yl)oxy)diphenylsilane
• CAS NO: 936724-58-2
• Molecular Weight: 378.63
• Mol File: 936724-58-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-tert-butyl((3,3-dimethylhepta-4,6-dien-1-yl)oxy)diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-tert-butyl((3,3-dimethylhepta-4,6-dien-1-yl)oxy)diphenylsilane(936724-58-2)
• EPA Substance Registry System: (E)-tert-butyl((3,3-dimethylhepta-4,6-dien-1-yl)oxy)diphenylsilane(936724-58-2)

Safety Data

• Hazardous Substances Data: 936724-58-2(Hazardous Substances Data)

Upstream product

• 1067-87-4 Diethyl allylphosphonate 
• 187869-61-0 4-(tert-butyldiphenysilanyloxy)-2,2-dimethylbutyraldehyde 
• 597-43-3 2,2-dimethylsuccinic acid 
• 32812-23-0 2,2-dimethylbutane-1,4-diol 
• 439693-30-8 4-{[tert-butyl(diphenyl)silyl]oxy}-2,2-dimethylbutan-1-ol 

Relevant articles and documents

A Palladium(II)-Catalyzed C-H Activation Cascade Sequence for Polyheterocycle Formation

Polyheterocycles are found in many natural products and are useful moieties in functional materials and drug design. As part of a program towards the synthesis of Stemona alkaloids, a novel palladium(II)-catalyzed C-H activation strategy for the construction of such systems has been developed. Starting from simple 1,3-dienyl-substituted heterocycles, a large range of polycyclic systems containing pyrrole, indole, furan and thiophene moieties can be synthesized in a single step. Don't overdo it: A palladium(II)-catalyzed C-H activation cascade sequence for the synthesis of polyheterocycles is reported. Aromatization of the initially formed dihydro species occurred with a quinone oxidant. In some cases the use of one equivalent of the oxidant enabled isolation of the dihydro species as a single isomer (see scheme; X=NMe, O, S).