936747-22-7

Basic information

• Product Name: (2-fluorophenyl)octylamine
• Synonyms: (2-fluorophenyl)octylamine
• CAS NO: 936747-22-7
• Molecular Weight: 223.334
• Mol File: 936747-22-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2-fluorophenyl)octylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (2-fluorophenyl)octylamine(936747-22-7)
• EPA Substance Registry System: (2-fluorophenyl)octylamine(936747-22-7)

Safety Data

• Hazardous Substances Data: 936747-22-7(Hazardous Substances Data)

Upstream product

• 348-54-9 2-Fluoroaniline 
• 111-83-1 1-bromo-octane 
• 629-05-0 n-octyne 
• 538-23-8 tricaprilin 

Relevant articles and documents

Esters, Including Triglycerides, and Hydrogen as Feedstocks for the Ruthenium-Catalyzed Direct N-Alkylation of Amines

Triglycerides are used for the direct N-alkylation of amines with molecular hydrogen for the first time. A broad range of interesting and industrially relevant secondary and tertiary amines are obtained in the presence of an in situ formed Ru/Triphos complex. Notably, plant oil can be efficiently applied in this single-step process. Moreover, a variety of other methyl esters can be used as N-alkylation agents in the presence of hydrogen for the synthesis of more advanced building blocks.

Aqueous-mediated N-alkylation of amines

Direct N-alkylation of primary amines to secondary/tertiary amines and of secondary amines to tertiary amines has been achieved in excellent yields by employing alkyl, benzylic and allylic halides in the presence of NaHCO 3 in an aqueous medium at an elevated temperature. Amines of different stereoelectronic nature react with ease with different halides. The selective formation of secondary amines and the formation of three different substituted tertiary amines are some of the interesting features of this methodology. Reaction in an aqueous medium, operationally convenient conditions, excellent yields and innocuous byproducts, and the absence of transition-metal catalysts, expensive bases, solid supports and the formation of undesired quaternary ammonium salts makes this method a green chemical process. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.