936845-85-1

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester
• Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester;tert-Butyl 4-(6-((5-formylthiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine-1-carboxylate
• CAS NO: 936845-85-1
• Molecular Formula: C18H24N6O3S
• Molecular Weight: 404.48656
• Mol File: 936845-85-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester(936845-85-1)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester(936845-85-1)

Safety Data

• Hazardous Substances Data: 936845-85-1(Hazardous Substances Data)

Usage

Description

1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester is a complex organic compound that belongs to the class of pyrimidines and pyrimidine derivatives. It is a derivative of piperazinecarboxylic acid and is commonly used in the synthesis of pharmaceuticals and agrochemicals. 1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester has shown potential as an antiviral and antifungal agent, and it also exhibits inhibitory activity against various enzymes. Due to its complex structure and potential therapeutic uses, it is of interest to researchers in the fields of medicinal chemistry and drug development.

Uses

Used in Pharmaceutical Industry:
1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester is used as an intermediate in the synthesis of pharmaceuticals for its potential antiviral and antifungal properties, as well as its inhibitory activity against various enzymes.
Used in Agrochemical Industry:
1-Piperazinecarboxylic acid, 4-[6-[(5-forMyl-2-thiazolyl)aMino]-2-Methyl-4-pyriMidinyl]-, 1,1-diMethylethyl ester is used as a component in the development of agrochemicals, where its antiviral and antifungal properties can be utilized for protecting crops and enhancing agricultural productivity.

Upstream product

• 1003-61-8 2-aminothiazole-5-carbaldehyde 
• 203519-37-3 tert-butyl 4-(6-chloro-2-methylpyrimidin-4-yl)piperazine-1-carboxylate 

Downstream Products

• 936845-86-2 4-[2-methyl-6-(5-vinyl-thiazol-2-ylamino)-pyrimidin-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 
• 936845-97-5 tert-butyl (E)-4-(6-((5-(3-methoxystyryl)thiazol-2-yl)amino)-2-methylpyrimidin-4-yl)piperazine-1-carboxylate 

Relevant articles and documents

THIAZOLE INHIBITORS TARGETING RESISTANT AND KINASE MUTATIONS

A compound is provided, having the general structure (A): wherein A is an aryl or heteroaryl group, Y is a hydrophobic linking moiety, and L is a substitutent. The compound (A) can be used for treatment of various angiogenic-associated or hematologic disorders, such as myeloproliferative disorders in patients who do not respond to kinase-inhibition therapy that comprises administering currently used medications.