936847-59-5

Basic information

• Product Name: methyl 4-(4-methyl-3-oxopentanamido)benzoate
• Synonyms: methyl 4-(4-methyl-3-oxopentanamido)benzoate
• CAS NO: 936847-59-5
• Molecular Weight: 263.293
• Mol File: 936847-59-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-(4-methyl-3-oxopentanamido)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(4-methyl-3-oxopentanamido)benzoate(936847-59-5)
• EPA Substance Registry System: methyl 4-(4-methyl-3-oxopentanamido)benzoate(936847-59-5)

Safety Data

• Hazardous Substances Data: 936847-59-5(Hazardous Substances Data)

Upstream product

• 42558-54-3 Methyl 4-methyl-3-oxopentanoate 
• 619-45-4 4-methoxycarbonyl aniline 

Downstream Products

• 936847-61-9 methyl 4-(2-(2-(4-fluorophenyl)-2-oxo-1-phenylethyl)-4-methyl-3-oxopentanamido)benzoate 
• 805241-61-6 methyl 4-(1-{2-[(4R,6R)-6-[2-(tert-butoxy)-2-oxoethyl]-2,2-dimethyl-1,3-dioxan-4-yl]ethyl}-5-(4-fluorophenyl)-4-phenyl-2-(propan-2-yl)-1H-pyrrole-3-amido)benzoate 
• 805241-63-8 tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-4-{[4-(hydroxymethyl)phenyl]carbamoyl}-3-phenyl-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 
• 936756-74-0 tert-butyl 2-[(4R,6R)-6-{2-[2-(4-fluorophenyl)-4-{[4-(hydroxymethyl)phenyl]carbamoyl}-3-phenyl-5-(propan-2-yl)-1H-pyrrol-1-yl]ethyl}-2,2-dimethyl-1,3-dioxan-4-yl]acetate 

Relevant articles and documents

METHOD OF PREPARING(3R,5R)-7-(2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-((4-HYDROXYMETHYLPHENYLAMINO)CARBONYL)-PYRROL-1-YL)-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT, AND METHOD OF PREPARING INTERMEDIATES USED THEREIN

The present invention provides a method for preparing (3R,5R)-7-(2-(4-flurophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrole-1-yl)-3,5-dihydroxy heptanoic acid hemicalcium salt. The preparation method of the present invention is performed in a convergent synthesis manner in which main structural moieties of a (3R,5R)-7-(2-(4-flurophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrole-1-yl)-3,5-dihydroxy heptanoic acid hemicalcium salt are independently synthesized, and then coupled. Accordingly, related substances can be easily controlled and preparing time can be reduced, thus improving the productivity of a compound, and the yield of a final compound can also be increased.