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936901-82-5

936901-82-5

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  • 4-(8-Chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)-1-piperidine carboxylic acid benzyl ester

    Cas No: 936901-82-5

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936901-82-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 936901-82-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,6,9,0 and 1 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 936901-82:
(8*9)+(7*3)+(6*6)+(5*9)+(4*0)+(3*1)+(2*8)+(1*2)=195
195 % 10 = 5
So 936901-82-5 is a valid CAS Registry Number.

936901-82-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)-1-piperidine carboxylate

1.2 Other means of identification

Product number -
Other names benzyl 4-(8-chloro-1-iodoimidazo[1,5-a]pyrazin-3-yl)piperidine-1-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:936901-82-5 SDS

936901-82-5Relevant articles and documents

Imidazo[1,5-a]pyrazines: Orally efficacious inhibitors of mTORC1 and mTORC2

Crew, Andrew P.,Bhagwat, Shripad V.,Dong, Hanqing,Bittner, Mark A.,Chan, Anna,Chen, Xin,Coate, Heather,Cooke, Andrew,Gokhale, Prafulla C.,Honda, Ayako,Jin, Meizhong,Kahler, Jennifer,Mantis, Christine,Mulvihill, Mark J.,Tavares-Greco, Paula A.,Volk, Brian,Wang, Jing,Werner, Douglas S.,Arnold, Lee D.,Pachter, Jonathan A.,Wild, Robert,Gibson, Neil W.

scheme or table, p. 2092 - 2097 (2011/04/24)

The discovery and optimization of a series of imidazo[1,5-a]pyrazine inhibitors of mTOR is described. HTS hits were optimized for potency, selectivity and metabolic stability to provide the orally bioavailable proof of concept compound 4c that demonstrate

UNSATURATED mTOR INHIBITORS

-

Page/Page column 48, (2010/11/28)

Compounds represented by Formula (I) or a pharmaceutically acceptable salt thereof, are inhibitors of mTOR and useful in the treatment of cancer.

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