937018-35-4 Usage
Description
4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside is a complex organic compound characterized by its unique structure, which includes a methylumbelliferyl core, three acetyl groups, and a trityl group attached to a β-D-glucopyranoside moiety. 4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside is known for its potential applications in various fields, particularly in organic synthesis.
Uses
Used in Organic Synthesis:
4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside is used as a synthetic intermediate for the preparation of various complex organic molecules. Its unique structure allows for selective functionalization and modification, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Analytical Chemistry:
4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside can also be employed as a chromogenic substrate in the development of assays for the detection and quantification of specific enzymes, such as glycosidases. The cleavage of the glycosidic bond by these enzymes releases the methylumbelliferone moiety, which exhibits fluorescence upon excitation, allowing for sensitive and specific detection of enzyme activity.
Used in Research and Development:
4’-Methylumbelliferyl 2,3,4,-Tri-O-acetyl-6-O-trityl-β-D-glucopyranoside serves as a valuable tool in academic and industrial research settings. It can be used to study the mechanisms of enzymatic reactions, investigate the properties of complex carbohydrates, and develop new synthetic methodologies for the preparation of biologically active compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 937018-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,3,7,0,1 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 937018-35:
(8*9)+(7*3)+(6*7)+(5*0)+(4*1)+(3*8)+(2*3)+(1*5)=174
174 % 10 = 4
So 937018-35-4 is a valid CAS Registry Number.
InChI:InChI=1/C41H38O11/c1-25-22-36(45)51-34-23-32(20-21-33(25)34)50-40-39(49-28(4)44)38(48-27(3)43)37(47-26(2)42)35(52-40)24-46-41(29-14-8-5-9-15-29,30-16-10-6-11-17-30)31-18-12-7-13-19-31/h5-23,35,37-40H,24H2,1-4H3/t35?,37-,38+,39+,40-/m1/s1
937018-35-4Relevant articles and documents
A new synthetic route to 4-methylumbelliferyl-β-D-glucopyranosiduronic acid (MUG)
López-López, Miguel A.,Balbuzano-Deus, Alexander,Rodríguez-Domínguez, Juan C.,Hernández, Miriam Mesa,Villalobo, Anais Fernández,Reyes, Yulianela Ibarra,Kirsch, Gilbert
, p. 649 - 651 (2007/10/03)
A synthetic route to prepare 4-methylumbelliferyl-β-D- glucopyranosiduronic acid (MUG) from 4-methylumbelliferyl-β-D- glucopyranoside (MUGluc) was developed. The primary hydroxyl group in MUGluc was protected by tritylation followed by acetylation of secondary hydroxyls. The triphenylmethyl group was selectively removed by treatment with iodine-methanol in benzene and the free hydroxyl was transformed into the carboxylic acid by phase-transfer oxidation with sodium hypochlorite and TEMPO as catalyst. Finally, the acetate groups were removed by reaction with barium methoxide in methanol to afford the MUG with an overall yield of 37% from the MUGluc. Georg Thieme Verlag Stuttgart.
