93710-17-9Relevant articles and documents
Synthesis of Dipeptide, Amide, and Ester without Racemization by Oxalyl Chloride and Catalytic Triphenylphosphine Oxide
Ren, Ji-Wei,Tong, Meng-Nan,Zhao, Yu-Fen,Ni, Feng
supporting information, p. 7497 - 7502 (2021/10/12)
An efficient triphenylphosphine oxide-catalyzed amidation and esterification for the rapid synthesis of a series of dipeptides, amides, and esters is described. This reaction is applicable to challenging couplings of hindered carboxylic acids with weakly
Fast Amide Couplings in Water: Extraction, Column Chromatography, and Crystallization Not Required
Sharma, Sudripet,Buchbinder, Nicklas W.,Braje, Wilfried M.,Handa, Sachin
supporting information, p. 5737 - 5740 (2020/07/14)
In the micelle of PS-750-M, the presence of 3° amides from the surfactant proline linker mimics dimethylformamide, dimethylacetamide, and N-methyl-2-pyrrolidone. The resultant micellar properties enable extremely fast amide couplings mediated by 1-ethyl-3
Iodine-Mediated Oxidative Coupling of Hydroxamic Acids with Amines towards a New Peptide-Bond Formation
Krishnamurthy, Muniyappa,Vishwanatha,Panguluri, Nageswara Rao,Panduranga,Sureshbabu, Vommina V.
supporting information, p. 2565 - 2569 (2015/11/16)
An efficient and straightforward approach for the coupling of Nα-protected hydroxamic acids with an amino component in the presence of iodine is delineated. The reaction is mediated by the formation of unstable but reactive acyl nitroso intermediates. The peptide hydroxamic acids were found to be useful substrates in coupling reactions.