93710-52-2

Basic information

• Product Name: (2-broMo-6-Methoxyphenyl)Methanol
• Synonyms: (2-broMo-6-Methoxyphenyl)Methanol;2-Bromo-6-methoxybenzyl alcohol
• CAS NO: 93710-52-2
• Molecular Formula: C₈H₉BrO₂
• Molecular Weight: 217.05986
• Mol File: 93710-52-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (2-broMo-6-Methoxyphenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-broMo-6-Methoxyphenyl)Methanol(93710-52-2)
• EPA Substance Registry System: (2-broMo-6-Methoxyphenyl)Methanol(93710-52-2)

Safety Data

• Hazardous Substances Data: 93710-52-2(Hazardous Substances Data)

Usage

Description

(2-broMo-6-Methoxyphenyl)Methanol, also known as 2-Bromo-6-methoxybenzyl alcohol, is an organic compound characterized by the presence of a bromine atom at the 2nd position and a methoxy group at the 6th position on a benzene ring. It also features a hydroxyl group attached to a methylene bridge, which connects to a phenyl group. This unique structure endows it with specific chemical properties and potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
(2-broMo-6-Methoxyphenyl)Methanol is used as a key intermediate in the synthesis of Pyrrolocarbazole derivatives for the treatment of Thrombopenia. Thrombopenia, or low blood platelet count, can lead to excessive bleeding and poses a significant health risk. Pyrrolocarbazole derivatives have demonstrated the ability to increase platelet count and improve the symptoms associated with Thrombopenia, making (2-broMo-6-Methoxyphenyl)Methanol an essential component in the development of these therapeutic agents.

Upstream product

• 31786-45-5 2-bromo-6-methoxybenzoic acid 
• 126712-07-0 2-bromo-6-methoxybenzaldehyde 
• 135-02-4 ortho-anisaldehyde 
• 124639-28-7 2-(2-methoxyphenyl)-1,3-dimethylimidazolidine 

Downstream Products

• 93710-53-3 2-bromo-6-methoxybenzylchloride 
• 93710-57-7 (2-bromo-6-methoxyphenyl)acetic acid 
• 93710-55-5 2-(2-bromo-6-methoxyphenyl)acetonitrile 
• 93710-63-5 N-(3-hydroxy-4-methoxyphenethyl)-2-(2-bromo-6-methoxyphenyl)acetamide 
• 93710-62-4 N-(3-benzyloxy-4-methoxyphenethyl)-2-(2-bromo-6-methoxyphenyl)acetamide 
• 126712-05-8 1-bromo-2-(bromomethyl)-3-methoxybenzene 
• 1242319-64-7 C₁₂H₁₈BrO₄P 
• 1242319-88-5 C₂₇H₂₃BrO₃ 
• 1431546-83-6 (E)-ethyl 3-(2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxyphenyl)acrylate 
• 1431546-82-5 ((2-bromo-6-methoxybenzyl)oxy)(tert-butyl)dimethyl silane 
• 1431546-84-7 (E)-3-(2-(((tert-butyldimethylsilyl)oxy)methyl)-3-methoxyphenyl)acrylic acid 

Relevant articles and documents

MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME

Described herein are monomers capable of forming a biologically useful multimer when in contact with one, two, three or more other monomers in an aqueous media. In one aspect, such monomers may be capable of binding to another monomer in an aqueous media (e.g. in vivo) to form a multimer, (e.g. a dimer). Contemplated monomers may include a ligand moiety, a linker element, and a connector element that joins the ligand moiety and the linker element. In an aqueous media, such contemplated monomers may join together via each linker element and may thus be capable of modulating one or more biomolecules substantially simultaneously, e.g., modulate two or more binding domains on a protein or on different proteins.

Total syntheses of dalesconol A and B

(Chemical equation Presented) (Chemical equation Presented) A polycyclic collapse: Use of a carefully designed acyclic intermediate participated in a cascade reaction that formed the entire core of the polyketide-derived dalesconols in a single flask (see scheme). A number of additional and carefully controlled synthetic operations completed an expeditious synthesis of both of these highly bioactive natural products as well as structural congenors.