93729-29-4

Basic information

• Product Name: 4-Oxazolecarboxylic acid, 2,5-diphenyl-, ethyl ester
• CAS NO: 93729-29-4
• Molecular Formula: C18H15NO3
• Molecular Weight: 293.322
• Mol File: 93729-29-4.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 4-Oxazolecarboxylic acid, 2,5-diphenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxazolecarboxylic acid, 2,5-diphenyl-, ethyl ester(93729-29-4)
• EPA Substance Registry System: 4-Oxazolecarboxylic acid, 2,5-diphenyl-, ethyl ester(93729-29-4)

Safety Data

• Hazardous Substances Data: 93729-29-4(Hazardous Substances Data)

Upstream product

• 23012-14-8 oxazole-4-carboxylic acid ethyl ester 
• 591-50-4 iodobenzene 
• 101735-38-0 (Z)-ethyl 2-benzamido-3-bromo-3-phenylacrylate 
• 101735-68-6 α-benzoylamino-β-chloro-cinnamic acid ethyl ester 
• 28383-65-5 ethyl 2-diazo-3-oxo-3-phenylpropanoate 
• 932-90-1 Benzaldoxime 
• 98-80-6 phenylboronic acid 
• 13433-00-6 diethyl aminomalonate hydrochloride 
• 84337-81-5 3-ethoxy-2-benzamido-3-oxopropanoic acid 
• 96-86-6 diethyl benzamidomalonate 
• 854180-71-5 5-oxo-2-phenyl-4,5-dihydro-oxazole-4-carboxylic acid ethyl ester 
• 34320-89-3 2-iodo-3-oxo-3-phenyl-propionic acid ethyl ester 
• 100-46-9 benzylamine 
• 100-47-0 benzonitrile 

Downstream Products

• 201033-47-8 4-Azidomethyl-2,5-diphenyl-oxazole 
• 90011-96-4 C-(2,5-Diphenyl-oxazol-4-yl)-methylamine 
• 132198-58-4 4-formyl-2,5-diphenyloxazole 
• 197719-35-0 2,5-Diphenyloxazole-4-carbonyl chloride 
• 113923-95-8 2,5-diphenyl-4-vinyloxazole 
• 573-34-2 2,4,5-triphenyloxazole 
• 400625-37-8 3-[4-(2,5-diphenyl-oxazol-4-ylmethoxy)-phenyl]-propan-1-ol 
• 400625-41-4 6-(2,5-diphenyl-oxazol-4-ylmethoxy)-hexan-1-ol 
• 400625-45-8 6-(2,5-diphenyl-oxazol-4-ylmethoxy)-hexanal 
• 133130-86-6 4-bromomethyl-2,5-diphenyloxazole 
• 94066-14-5 2,5-diphenyl-oxazole-4-carboxylic acid hydrazide 
• 2549-35-1 2,5-diphenyl-4-hydroxymethyloxazole 
• 18735-78-9 2,5-diphenyloxazole-4-carboxylic acid 

Relevant articles and documents

Effective C5-Arylation of Peptide-Integrated Oxazoles: Almazole D

An efficient functionalization approach of oxazoles by using Pd-catalyzed cross-coupling reactions is reported. Oxazolone formation and subsequent sulfamoylation in situ are facilitated by employing N,N-diethylsulfamoyl imidazolium triflate. Cross-couplings provide both oxazole-arenes and oxazole-heteroarenes and were compatible with sensitive and epimerization-prone substrates, as exemplified by the total synthesis of the natural product almazole D. (Figure presented.).

Electrochemical Iodine-Mediated Oxidation of Enamino-Esters to 2H-Azirine-2-Carboxylates Supported by Design of Experiments

An electrochemical iodine-mediated transformation of enamino-esters for the synthesis of 2H-azirine-2-carboxylates is presented. In addition, a thermic conversion of azirines to 4-carboxy-oxazoles in quantitative yield without purification was described.

A Gold-Catalyzed Acid-Assisted Regioselective Cyclization for the Synthesis of Polysubstituted Oxazoles

Polysubstituted oxazole derivatives are obtained through a regioselective gold-catalyzed reaction of α-alkynylamides and alkynoates in the presence of nitriles. The intermediary obtained gold carbenes are generated by alkyne oxidation with a pyridine N-oxide. Acidic conditions ensure that only one of the two carbonyl oxygen atoms in these intermediates selectively cyclizes to the products in excellent yields.