937701-79-6

Basic information

• Product Name: (S)-N-((1-Boc-pyrrolidin-2-yl)-methyl)-2-aminobenzamide
• Synonyms: (S)-N-((1-Boc-pyrrolidin-2-yl)-methyl)-2-aminobenzamide
• CAS NO: 937701-79-6
• Molecular Weight: 319.404
• Mol File: 937701-79-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-N-((1-Boc-pyrrolidin-2-yl)-methyl)-2-aminobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-((1-Boc-pyrrolidin-2-yl)-methyl)-2-aminobenzamide(937701-79-6)
• EPA Substance Registry System: (S)-N-((1-Boc-pyrrolidin-2-yl)-methyl)-2-aminobenzamide(937701-79-6)

Safety Data

• Hazardous Substances Data: 937701-79-6(Hazardous Substances Data)

Upstream product

• 1254178-79-4 (S)-1-Boc-2-((2-nitrobenzamido)methyl)pyrrolidine 
• 118-48-9 isatoic anhydride 
• 119020-01-8 (S)-2-(aminomethyl)pyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 937701-81-0 C₁₇H₂₄N₃O₃COCCHCHNC₆H₄ 
• 937701-87-6 C₂₂H₂₂N₄O₂ 

Relevant articles and documents

Functionalized proline with double hydrogen bonding potential: Highly enantioselective Michael addition of carbonyl compounds to β-nitrostyrenes in brine

Simple synthetic manipulation of S-proline allows access to prolinamides 5-7 as organocatalysts capable of double hydrogen bonding for enantioselective Michael addition reactions of carbonyl compounds to β-nitrostyrenes. It is shown that prolinamide catalyst 7 leads to addition products with a high diastereo- as well as enantioselectivity. The transition state structure involving the binding of electrophilic nitrostyrene via two H-bonds is believed to be further stabilized by π,π stacking interactions mediated by the tosyl ring.