937740-19-7Relevant articles and documents
Facile synthesis of (±)-paeonilide
Du, Yuguo,Liu, Jun,Linhardt, Robert J.
, p. 3952 - 3954 (2008/02/01)
(Chemical Equation Presented) (±)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis.