93794-39-9

Basic information

• Product Name: 2-chloro-6-methoxybenzo[d]oxazole
• Synonyms: 2-chloro-6-methoxybenzo[d]oxazole;2-chloro-6-methoxy-benzoxazole;2-CHLORO-6-METHOXY-1,3-BENZOXAZOLE
• CAS NO: 93794-39-9
• Molecular Formula: C₈H₆ClNO₂
• Molecular Weight: 183.59174
• Mol File: 93794-39-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-chloro-6-methoxybenzo[d]oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-methoxybenzo[d]oxazole(93794-39-9)
• EPA Substance Registry System: 2-chloro-6-methoxybenzo[d]oxazole(93794-39-9)

Safety Data

• Hazardous Substances Data: 93794-39-9(Hazardous Substances Data)

Upstream product

• 13895-04-0 6-methoxybenzo[d]oxazole-2(3H)-thione 
• 13895-04-0 6-methoxybenzo[d]oxazole-2-thiol 
• 40925-70-0 2-amino-5-methoxyphenol 
• 140-90-9 sodium O-ethyl dithiocarbonate 
• 39547-15-4 1-amino-2-hydroxy-4-methoxybenzene hydrochloride 
• 150-19-6 O-methylresorcine 
• 704-14-3 3-methoxy-6-nitro-phenol 

Downstream Products

• 532-91-2 coixol 
• 1334386-03-6 (S)-2-(2-hydroxy-4-methoxyphenylamino)-thiazoline-5,5-dimethyl-4-carboxylic acid trifluoroacetate 
• 1334386-20-7 (R)-2-(2-hydroxy-4-methoxyphenylamino)-thiazoline-4-carboxylic acid hydrochloride 
• 1334386-19-4 (R)-2-(6-methoxybenzoxazol-2-ylamino)-3-tritylsulfanyl-propionic acid 

Relevant articles and documents

HMOX1 inducers

The present invention is related to compounds of structure (I) as heme oxygenase 1 (HMOX 1) inducers. The present invention is also related a method of controlling the activity or the amount, or both the activity and the amount, of heme-oxygenase 1 in a mammalian subject. The definitions of the variables are provided herein.

Analgesic Compounds, Compositions, and Uses Thereof

The invention relates to compounds, compositions, and methods for diminishing pain in a subject in need thereof comprising administering the compounds and compositions herein described.

A new 5-HT3 receptor ligand. II. Structure-activity analysis of 5-HT3 receptor agonist action in the gut

Several modified 2-piperazinyl benzoxazole derivatives, which exhibit an agonistic effect on gastrointestinal motility, were synthesized and their effects on the contraction of guinea-pig ileum were examined. The quaternary piperazinyl benzoxazole structure has a restricted conformation and stereostructure compared to those of the other 5-HT3 receptor agonists, serotonin and meta-chlorophenylbiguanide. The mutual positions of the aromatic ring, nitrogen atom and terminal amine are considered to form the pharmacophore of the 5-HT3 receptor agonist in the gut. In the serotonin- evoked reflex bradycardia [Bezold-Jarisch (B-J) reflex] inhibition test using rats the B-J reflex-inducing ratio was different for each synthesized compound. These results suggest that, in these 5-HT3 receptor agonists, the substituents of the benzoxazole ring influence the B-J reflex-inducing activity in rats.