938056-62-3Relevant articles and documents
Highly diastereoselective alkylation of aziridine-2-carboxylate esters: Enantioselective synthesis of LFA-1 antagonist BIRT-377
Patwardhan, Aniruddha P.,Pulgam, V. Reddy,Zhang, Yu,Wulff, William D.
, p. 6169 - 6172 (2005)
The benzhydryl group is the key: Efficient alkylation of 3-substituted aziridine-2-carboxylates is only possible with N-benzhydryl-protected aziridines and occurs with complete retention of the configuration at the 2-position. Sequential catalytic asymmet