938174-17-5Relevant articles and documents
Synthesis and biological activity of allosteric modulators of GABA B receptors, Part 2. 3-(2,6-Bis-tert-butyl-4-hydroxyphenyl)propanols
Kerr, David I. B.,Khalafy, Jabbar,Ong, Jennifer,Perkins, Michael V.,Prager, Rolf H.,Puspawati, Ni Made,Rimaz, Mehdi
, p. 457 - 462 (2007/10/03)
A series of 13 2,2-disubstituted 3-(3,5-di-t-butyl-4-hydroxyphenyl)propan- 1-ol derivatives have been prepared for evaluation as allosteric modulators of GABAB receptors. The activity (EC50, 4?7 ?M) was greatest for the cyclohexyl and cyclopentyl analogues. CSIRO 2006.