93840-49-4Relevant articles and documents
Synthesis of novel chiral monophosphine ligands derived from isomannide and isosorbide. Application to enantioselective hydrogenation of olefins
Ibrahim, Houssein,Bournaud, Chloée,Guillot, Régis,Toffano, Martial,Vo-Thanh, Giang
supporting information; experimental part, p. 4900 - 4902 (2012/09/21)
A new class of monophosphine ligands has been prepared from natural chirality renewable source, 1,4:3,6-dianhydrohexitol compounds, via a nucleophilic substitution process, or a hydrophosphination reaction involving microwave activation. These ligands have been evaluated for the rhodium-catalyzed enantioselective hydrogenation of olefins giving good conversion and enantioselectivity up to 95% and 96% ee, respectively.