938443-86-8

Basic information

• Product Name: methyl 3-phenylbenzofuran-2-carboxylate
• Synonyms: methyl 3-phenylbenzofuran-2-carboxylate
• CAS NO: 938443-86-8
• Molecular Weight: 252.269
• Mol File: 938443-86-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl 3-phenylbenzofuran-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-phenylbenzofuran-2-carboxylate(938443-86-8)
• EPA Substance Registry System: methyl 3-phenylbenzofuran-2-carboxylate(938443-86-8)

Safety Data

• Hazardous Substances Data: 938443-86-8(Hazardous Substances Data)

Upstream product

• 1558-67-4 formic anhydride 
• 186395-08-4 methyl 2-(2-iodophenoxy)acetate 
• 98-80-6 phenylboronic acid 
• 90-02-8 salicylaldehyde 
• 108-86-1 bromobenzene 
• 1646-27-1 methyl benzofuran-2-carboxylate 
• 22367-83-5 ethyl 3-phenyl-1-benzofuran-2-carboxylate 
• 117-99-7 2-Hydroxybenzophenone 
• 186581-53-3 diazomethane 
• 60312-24-5 PL-158 

Downstream Products

• 110421-04-0 3-phenyl-benzofuran-2-carbaldehyde-(2,4-dinitro-phenylhydrazone) 
• 111272-52-7 N-benzenesulfonyl-N'-(3-phenyl-benzofuran-2-carbonyl)-hydrazine 
• 119925-59-6 2-phenyl-4-(3-phenyl-benzofuran-2-ylmethylen)-4H-oxazol-5-one 
• 111327-99-2 3-phenyl-benzofuran-2-carbaldehyde semicarbazone 
• 57329-33-6 3-phenyl-1-benzofuran-2-carbaldehyde 
• 109507-95-1 3-phenyl-benzofuran-2-carboxylic acid hydrazide 

Relevant articles and documents

Facile benzofuran synthesis: Palladium-catalyzed carbonylative Suzuki coupling of methyl 2-(2-iodophenoxy)acetates under CO gas-free conditions

A palladium-catalyzed carbonylative Suzuki coupling of methyl 2-(2-iodophenoxy)acetates with arylboronic acids has been developed. The reactions were performed under CO gas-free conditions and the obtained products act as a direct precursor for the synthesis of highly functionalized benzofuran derivatives.

Palladium-catalyzed direct arylation of polysubstituted benzofurans

An efficient access to 2-substituted 3-arylbenzofurans through a palladium-catalyzed C3 direct arylation of 2-substituted benzofurans with aryl bromides is described. The scope and limitation of this reaction was studied. The method tolerates a variety of functional groups on the aryl halide and has been successfully extended to polysubstituted benzofurans to obtain the corresponding 3-arylbenzofurans with good to excellent yields.