93865-36-2

Basic information

• Product Name: 4-Piperidinamine, 1-benzoyl-N,N-dimethyl-
• CAS NO: 93865-36-2
• Molecular Formula: C14H20N2O
• Molecular Weight: 232.326
• Mol File: 93865-36-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Piperidinamine, 1-benzoyl-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinamine, 1-benzoyl-N,N-dimethyl-(93865-36-2)
• EPA Substance Registry System: 4-Piperidinamine, 1-benzoyl-N,N-dimethyl-(93865-36-2)

Safety Data

• Hazardous Substances Data: 93865-36-2(Hazardous Substances Data)

Upstream product

• 84157-05-1 phenyl(1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methanone 
• 177-11-7 4,4-ethylenedioxy-piperidine 
• 98-88-4 benzoyl chloride 
• 24686-78-0 1-Benzoyl-4-piperidone 
• 124-40-3 dimethyl amine 

Downstream Products

• 64168-08-7 1-benzyl-N,N-dimethylpiperidin-4-amine 

Relevant articles and documents

Antinociceptive effects of 1-acyl-4-dialkylaminopiperidine and 1-alkyl-4-dialkylaminopiperidine in mice: Structure-activity relation study of matrine-type alkaloids

We previously reported that (+)-matrine and (+)-allomatrine have antinociceptive properties mediated mainly through the activation of κ-opioid receptors. 1-Acyl-4-dialkylaminopiperidines were synthesized as the simplest derivatives of matrine, and the structure-activity relations were examined by the acetic acid-induced abdominal contraction test. The antinociceptive potencies of 1-alkyl-4-dialkylaminopiperidines were significantly lower than those of the corresponding 1-acyl-4- dialkylaminopiperidines. These findings suggest that the amide group of (+)-matrine is an essential functional group that influences antinociceptive potency.