93923-90-1

Basic information

• Product Name: erythro-5-hydroxy-L-lysine monohydrochloride
• Synonyms: erythro-5-Hydroxy-L-lysine monohydrochloride; erythro-5-Hydroxy-L-lysine HCl; (2S,5S)-2,6-diamino-5-hydroxy-hexanoic acid hydrochloride
• CAS NO: 93923-90-1
• Molecular Formula: C₆H₁₄N₂O₃*ClH
• Molecular Weight: 198.6479
• EINECS: 300-180-3
• Mol File: 93923-90-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 432.8°C at 760 mmHg
• Flash Point: 215.5°C
• Vapor Pressure: 2.63E-09mmHg at 25°C
• CAS DataBase Reference: erythro-5-hydroxy-L-lysine monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: erythro-5-hydroxy-L-lysine monohydrochloride(93923-90-1)
• EPA Substance Registry System: erythro-5-hydroxy-L-lysine monohydrochloride(93923-90-1)

Safety Data

• Hazardous Substances Data: 93923-90-1(Hazardous Substances Data)

Upstream product

• 753010-16-1 tert-butyl (3S,5S,6R)-3-[(3R)-4-azido-3-hydroxybutyl]-2-oxo-5,6-diphenyl-1,4-oxazine-4-carboxylate 
• 144542-72-3 (3S,5S,6R)-4-(tert-butyloxycarbonyl)-5,6-diphenyl-3-(3'-butenyl)-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one 
• 937183-38-5 tert-butyl (3S,5S,6R)-3-(2-((RS)oxiran-2-yl)ethyl)-2-oxo-5,6-diphenylmorpholine-4-carboxylate 
• 753010-18-3 tert-butyl (3S,5S,6R)-3-[(3R)-3-hydroxy-4-iodobutyl]-2-oxo-5,6-diphenyl-1,4-oxazine-4-carboxylate 

Relevant articles and documents

A practical and simple synthesis of (2S,5R)- and (2S,5S)-5-hydroxylysine and of a related α-amino acid required for the synthesis of the collagen cross-link pyridinoline

A four step synthesis of (2S,5R)- and (2S,5S)-5-hydroxylysine using Williams' glycine template methodology for controlling the stereogenicity at the α-position is reported. This route offers the possibility for the synthesis of all possible isomers of 5-hydroxylysine and of an important α-amino acidic iodohydrin required for the construction of the hydroxylated side chain of the collagen cross-link pyridinoline.