939437-01-1

Basic information

• Product Name: diethyl N-[4-[(2-2,4-diamino-5,10-methylene-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl methyl)amino]benzoyl]-L-glutamate
• Synonyms: diethyl N-[4-[(2-2,4-diamino-5,10-methylene-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl methyl)amino]benzoyl]-L-glutamate
• CAS NO: 939437-01-1
• Molecular Weight: 511.581
• Mol File: 939437-01-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diethyl N-[4-[(2-2,4-diamino-5,10-methylene-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl methyl)amino]benzoyl]-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl N-[4-[(2-2,4-diamino-5,10-methylene-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl methyl)amino]benzoyl]-L-glutamate(939437-01-1)
• EPA Substance Registry System: diethyl N-[4-[(2-2,4-diamino-5,10-methylene-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl methyl)amino]benzoyl]-L-glutamate(939437-01-1)

Safety Data

• Hazardous Substances Data: 939437-01-1(Hazardous Substances Data)

Upstream product

• 76822-61-2 2,4-Diamino-6-(hydroxymethyl)pyrido<3,2-d>pyrimidine 
• 76807-55-1 6-(Acetoxymethyl)-2,4-dichloropyrido<3,2-d>pyrimidine 
• 13726-52-8 diethyl N-(p-aminobenzoyl)-L-glutamate 
• 50-00-0 formaldehyd 
• 939436-99-4 diethyl N-[4-[[2-(2,4-diamino-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino]benzoyl]-L-glutamate 
• 76807-59-5 Diethyl 8-Deazaaminopterin 
• 76807-56-2 2,4-diamino-6-(bromomethyl)pyrido<3,2-d>pyrimidine 

Relevant articles and documents

Mechanism-based design, synthesis and biological studies of N 5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents

A number of 8-deazatetrahydrofolates bearing electrophilic groups on N 5 were designed and synthesized based on the action mechanism of methionine synthase, and their biological activities were investigated as well. Compounds (11b, 12b and 16)