939983-14-9

Basic information

• Product Name: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone
• Synonyms: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone;p53 and MDM2 proteins-interaction-inhibitor (raceMic);Ethanone, 2-[4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-diMethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-diMethyl-1H-iMidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-Morpholinyl)-;p53 inhibitor (raceMic);2-(4-((4R,5S)-2-(4-(tert-Butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dime hyl-4,5-dihydro-;2-(4-((4R,5S)-2-(4-(tert-Butyl)-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimehyl-4,5-dihydr
• CAS NO: 939983-14-9
• Molecular Formula: C40H49Cl2N5O4
• Molecular Weight: 734.75416
• Mol File: 939983-14-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.24
• CAS DataBase Reference: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone(939983-14-9)
• EPA Substance Registry System: rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone(939983-14-9)

Safety Data

• Hazardous Substances Data: 939983-14-9(Hazardous Substances Data)

Usage

General Description

The chemical "rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone" is a complex compound with a long name. It contains various functional groups such as piperazinyl and morpholinyl, and a carbonyl group linked to the imidazol-1-yl group. The compound also contains phenyl groups with chloro substitutions and an ethoxy group. rel-2-[4-[[(4R,5S)-4,5-Bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-4,5-dimethyl-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-1-(4-morpholinyl)ethanone likely has specific pharmaceutical or biological activities due to its complex structure, which makes it a potentially interesting target for medical research. However, further analysis and studies would be needed to determine its exact properties and potential applications.

Upstream product

• 939981-37-0 (4S,5R)-4-[[4-[[4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxy-phenyl]-4,5-dimethyl-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]acetyl]-morpholine 
• 39890-46-5 1-morpholino-2-(piperazin-1-yl)ethanone 
• 939983-16-1 meso-2,3-bis-(4-chlorophenyl)-2,3-butanediamine 
• 1313703-90-0 (4S*,5R*)-4,5-bis(4-chlorophenyl)-2-(4-(tert-butyl)-2-ethoxy-phenyl)-4,5-dimethyl-4,5-dihydro-1H-imidazole 
• 870007-39-9 4-(tert-butyl)-2-ethoxy-benzoic acid methyl ester 

Relevant articles and documents

Discovery of RG7112: A small-molecule MDM2 inhibitor in clinical development

The p53 tumor suppressor is a potent transcription factor that plays a key role in the regulation of cellular responses to stress. It is controlled by its negative regulator MDM2, which binds directly to p53 and inhibits its transcriptional activity. MDM2