939999-41-4

Basic information

• Product Name: N-hydroxy-3-(methylsulfonyl)benzamidine
• Synonyms: N-hydroxy-3-(methylsulfonyl)benzamidine;Benzenecarboximidamide, N-hydroxy-3-(methylsulfonyl)-;N'-hydroxy-3-(methylsulfonyl)benzenecarboximidamide
• CAS NO: 939999-41-4
• Molecular Formula: C₈H₁₀N₂O₃S
• Molecular Weight: 214.2416
• Mol File: 939999-41-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-hydroxy-3-(methylsulfonyl)benzamidine(CAS DataBase Reference)
• NIST Chemistry Reference: N-hydroxy-3-(methylsulfonyl)benzamidine(939999-41-4)
• EPA Substance Registry System: N-hydroxy-3-(methylsulfonyl)benzamidine(939999-41-4)

Safety Data

• Hazardous Substances Data: 939999-41-4(Hazardous Substances Data)

Upstream product

• 22821-75-6 3-(methylsulfonyl)benzonitrile 

Downstream Products

• 1166829-07-7 4-(1-(2-fluorophenyl)-4-{3-[3-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1H-1,2,3-triazol-5-yl)pyridine 
• 1258008-56-8 2-{3-[3-(methylsulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-pyridin-4-ylethanone 

Relevant articles and documents

KCNT1 INHIBITORS AND METHODS OF USE

The present invention is directed to, in part, compounds and compositions useful for preventing and/or treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene (e.g., KCNT1). Methods of treating a neurological disease or disorder, a disease or condition relating to excessive neuronal excitability, and/or a gain-of-function mutation in a gene such as KCNT1 are also provided herein.

OXADIAZOLE DERIVATIVES

The invention relates to compounds of formula (I): wherein R1, R2, Ra, Rb, W, Q and S have the meanings given in claim 1. The compounds are useful e.g. in the treatment of autoimmune disorders, such as multiple sclerosis.