940-04-5

Basic information

• Product Name: 1-(4-hydroxy-3-methylphenyl)propan-1-one
• CAS NO: 940-04-5
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2011
• Mol File: 940-04-5.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 313.6°C at 760 mmHg
• Flash Point: 132.8°C
• Density: 1.079g/cm³
• Vapor Pressure: 0.000268mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 1-(4-hydroxy-3-methylphenyl)propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-hydroxy-3-methylphenyl)propan-1-one(940-04-5)
• EPA Substance Registry System: 1-(4-hydroxy-3-methylphenyl)propan-1-one(940-04-5)

Safety Data

• Hazardous Substances Data: 940-04-5(Hazardous Substances Data)

Usage

Description

1-(4-hydroxy-3-methylphenyl)propan-1-one, also known as p-hydroxyacetophenone, is an organic compound belonging to the class of ketones. It features a phenolic structural motif and is derived from acetophenone. This chemical is characterized by its potential applications in various industries due to its unique properties.

Uses

Used in Pharmaceutical Industry:
1-(4-hydroxy-3-methylphenyl)propan-1-one is used as a chemical intermediate for the synthesis of various drugs. Its application in this industry is driven by its ability to contribute to the development of new medications.
1-(4-hydroxy-3-methylphenyl)propan-1-one is also used as a source of potential anti-inflammatory and antioxidant properties, which can be harnessed for the creation of pharmaceutical products aimed at treating specific health conditions.
Used in Perfumery Industry:
In the perfumery industry, 1-(4-hydroxy-3-methylphenyl)propan-1-one is used to impart a floral and sweet aroma to fragrances. Its application is based on its capacity to enhance the sensory experience of perfumes by adding a pleasant and distinctive scent.
Used in Flavoring Industry:
Similarly, in the flavoring industry, 1-(4-hydroxy-3-methylphenyl)propan-1-one is utilized to give a floral and sweet taste to various products. Its application is justified by its ability to improve the flavor profile and create a more appealing taste sensation for consumers.

Upstream product

• 76805-57-7 3-methyl-4-methoxypropiophenone 
• 802294-64-0 propionic acid 
• 95-48-7 ortho-cresol 
• 65648-53-5 1-Methoxy-3-trimethylsilyloxy-1,3-pentadein 
• 7497-88-3 propionic acid o-toluyl ester 
• 3338-15-6 1-(2-hydroxy-3-methyl-phenyl)-propan-1-one 
• 7446-70-0 aluminium trichloride 
• 98-95-3 nitrobenzene 
• 905911-50-4 1-[3-methyl-4-(2-trimethylsilanyl-ethoxymethoxy)-phenyl]-propan-1-one 
• 79-03-8 propionyl chloride 

Downstream Products

• 18441-56-0 2-methyl-4-propylphenol 
• 77053-38-4 3,4-bis-(4-hydroxy-3-methyl-phenyl)-hexane-3,4-diol 
• 137937-51-0 1-(3-methyl-4-propionyloxy-phenyl)-propan-1-one 
• 2887-58-3 1-(4-hydroxy-3-methyl-phenyl)-propan-1-one-(2,4-dinitro-phenylhydrazone) 
• 3275-77-2 3-Methyl-4-(2-dimethylamino-ethoxy)-propiophenon 
• 1939-67-9 1-[4-(2,3-dihydroxy-propoxy)-3-methyl-phenyl]-propan-1-one 
• 4481-50-9 3,4-bis-(4-hydroxy-3-methyl-phenyl)-hexa-2,4-diene 
• 93406-90-7 phenyl-carbamic acid-(2-methyl-4-propyl-phenyl ester) 
• 1940-64-3 1-(2,3-Dihydroxy-propoxy)-4-(1-hydroxy-propyl)-2-methyl-benzol 
• 905911-51-5 2-methyl-2-(2-methyl-4-propionyl-phenoxy)-propionic acid ethyl ester 
• 1268705-04-9 (E)-ethyl 2-(4-(1-(hydroxyimino)propyl)-2-methylphenoxy)acetate 
• 1268705-15-2 (E)-ethyl 2-(2-methyl-4-(1-(((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)imino)propyl)phenoxy)acetate 
• 1268705-22-1 (E)-2-(2-methyl-4-(1-(((4-methyl-2-(4-(trifluoromethyl)phenyl)thiazol-5-yl)methoxy)imino)propyl)phenoxy)acetic acid 

Relevant articles and documents

TETRAZOLINONE COMPOUND AND APPLICATION OF SAME

A tetrazolinone compound represented by formula (1): wherein R1 represents a C1-C3 alkyl group optionally having a fluorine atom, etc.; R2 and R4 represents a hydrogen atom, etc.; R3 represents a hydrogen atom,

TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF

Disclosed is a tetrazolinone compound having a high pest control effect and represented by the formula (1): wherein R1, R2, R3, and R11 each represent a halogen atom, a C1-C6 alkyl group, or the like; R4 and R5 each represent a hydrogen atom, a halogen atom, a C1-C3 alkyl group, or the like; R6 represents a C1-C3 alkyl group which may have a halogen atom(s) or the like; R7, R8, and R9 each represent a hydrogen atom, a halogen atom, or the like; R10 represents a C1-C3 alkyl group or the like; R12 represents a C1-C6 alkyl group, a C3-C6 cycloalkyl group, or the like, and R13 represents a C1-C6 alkyl group, a C2-C6 alkenyl group, or the like.

Ethacrynic acid analogues lacking the α,β-unsaturated carbonyl unit-Potential anti-metastatic drugs

A series of ethacrynic acid analogues, lacking the α,β-unsaturated carbonyl unit, was synthesized and subsequently evaluated for their ability to inhibit the migration of human breast cancer cells, MCF-7/AZ. Several of the analogues were already active in the low micromolar range, whereas ethacrynic acid itself shows no potential to inhibit the migration of these cancer cells. Preliminary studies show that the presence of one or more methoxy groups at the phenyl ring of ethacrynic acid is important in order for the ethacrynic acid analogues to demonstrate an inhibitory effect on the migration.