940000-26-0

Basic information

• Product Name: (R)-1-N-BOC-2-CYANO-PIPERIDINE
• Synonyms: (R)-2-CYANO-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(R)-1-N-BOC-2-CYANO-PIPERIDINE;(R)-TERT-BUTYL 2-CYANOPIPERIDINE-1-CARBOXYLATE;1-N-BOC-2-(R)-CYANO-PIPERIDINE;(R)-1-Boc-2-cyanopiperidine;(R)-N-Boc-2-cyanopiperidine;tert-butyl (2R)-2-cyanopiperidine-1-carboxylate;(2R)-2-Cyano-1-piperidinecarboxylic acid tert-butyl ester
• CAS NO: 940000-26-0
• Molecular Formula: C11H18N2O2
• Molecular Weight: 210.27
• Mol File: 940000-26-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 325.3 °C at 760 mmHg
• Flash Point: 150.5 °C
• Appearance: /
• Density: 1.07
• Vapor Pressure: 0.000232mmHg at 25°C
• Refractive Index: 1.487
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (R)-1-N-BOC-2-CYANO-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-N-BOC-2-CYANO-PIPERIDINE(940000-26-0)
• EPA Substance Registry System: (R)-1-N-BOC-2-CYANO-PIPERIDINE(940000-26-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3439
• Hazardous Substances Data: 940000-26-0(Hazardous Substances Data)

Usage

General Description

"(R)-1-N-BOC-2-CYANO-PIPERIDINE" is a chemical compound used in the synthesis of various pharmaceuticals and other organic compounds. It is a piperidine derivative with a BOC (tert-butyloxycarbonyl) protecting group at the nitrogen atom and a cyano group attached to the 2-position of the piperidine ring. (R)-1-N-BOC-2-CYANO-PIPERIDINE is an important intermediate in the production of various drugs, including antiviral and antibacterial agents, as well as other biologically active molecules. It is commonly used in organic synthesis and medicinal chemistry research due to its versatile reactivity and utility in building complex molecules.

InChI:InChI=1/C11H18N2O2/c1-11(2,3)15-10(14)13-7-5-4-6-9(13)8-12/h9H,4-7H2,1-3H3/t9-/m1/s1

Upstream product

• 28697-17-8 N-BOC-D-pipecolic acid 
• 848488-91-5 tert-butyl (R)-2-carbamoylpiperidine-1-carboxyl-ate 

Relevant articles and documents

POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY

The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Z1 is NR4; R1 is hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SO2 and NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; R2 is optionally substituted aryl; R3 is hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and R4 and Z2 part taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound.