94011-49-1

Basic information

• Product Name: Propanedioic acid, (2-oxo-2-phenylethyl)-, diethyl ester
• Synonyms: phenacyl-malonic acid diethyl ester;Phenacyl-malonsaeure-diaethylester;ethyl 2-ethoxycarbonyl-4-phenyl-4-oxo-butyrate;Propanedioic acid,(2-oxo-2-phenylethyl)-,diethyl ester;diethyl phenacylmalonate;diethyl (2-oxo-2-phenylethyl)propanedioate;diethyl 2-(2-oxo-2-phenylethyl)malonate
• CAS NO: 94011-49-1
• Molecular Formula: C15H18O5
• Molecular Weight: 278.305
• Mol File: 94011-49-1.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (2-oxo-2-phenylethyl)-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (2-oxo-2-phenylethyl)-, diethyl ester(94011-49-1)
• EPA Substance Registry System: Propanedioic acid, (2-oxo-2-phenylethyl)-, diethyl ester(94011-49-1)

Safety Data

• Hazardous Substances Data: 94011-49-1(Hazardous Substances Data)

Upstream product

• 996-82-7 sodium diethylmalonate 
• 64-17-5 ethanol 
• 70-11-1 α-bromoacetophenone 
• 996-82-7 sodium diethylmalonate 
• 28531-58-0 (2-oxo-2-phenylethyl)mercury chloride 
• 14851-10-6 bis-ethoxycarbonyl-methanide 
• 14548-16-4 Dimethyl-(1-phenyl-vinyl)-amine 
• 685-87-0 Diethyl 2-bromomalonate 
• 71639-13-9 diethyl 2-(3-nitrophenylethyl)malonate 
• 98-86-2 acetophenone 
• 105-53-3 diethyl malonate 
• 28143-79-5 1-phenyl vinyl triflate 
• 78386-38-6 1-tert-butoxy-1-phenylethene 
• 532-27-4 1-chloroacetophenone 

Downstream Products

• 861330-73-6 2-oxo-5-phenyl-2,3-dihydro-furan-3-carboxylic acid ethyl ester 
• 118418-47-6 4,4-bis(ethoxycarbonyl)-2-phenylbicyclo<3.2.0>hept-1-ene 
• 115399-25-2 3-Methyl-1-oxo-6-phenyl-1,3,3a,5-tetrahydro-cyclopenta[c]furan-4,4-dicarboxylic acid diethyl ester 
• 115399-24-1 1-Oxo-6-phenyl-1,3,3a,5-tetrahydro-cyclopenta[c]furan-4,4-dicarboxylic acid diethyl ester 
• 94011-50-4 ethyl 3-oxo-6-phenyl-2,3,4,5-tetrahydropyridazine-4-carboxylate 
• 147322-00-7 3-hydroxymethyl-1-phenylbutan-1,4-diol 
• 213838-31-4 N-(2',3',4',6'-tetra-O-acetyl-β-D-glucopyranosyl)-2,2-diethoxycarbonyl-4-phenyl-4-oxothiobutanamide 
• 213838-35-8 5-Phenyl-2-thioxo-1-((2R,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yl)-1,2-dihydro-pyrrole-3,3-dicarboxylic acid diethyl ester 
• 159162-45-5 5-(2-hydroxyl-2-phenylethyl)-2,2-dimethyl-1,3-dioxane 
• 159162-49-9 5-(2-hydroxy-2-phenylethyl)-2-phenyl-1,3-dioxane 
• 159162-46-6 Phosphorous acid 2-(2,2-dimethyl-[1,3]dioxan-5-yl)-1-phenyl-ethyl ester dimethyl ester 
• 159162-47-7 [2-(2,2-Dimethyl-[1,3]dioxan-5-yl)-1-phenyl-ethyl]-phosphonic acid dimethyl ester 

Relevant articles and documents

Cu(OAc)2-Triggered Cascade Reaction of Malonate-Tethered Acyl Oximes with Indoles, Indole-2-alcohols, and Indole-2-carboxamides

A Cu(OAc)2-promoted cascade reaction of malonate-tetherd acyl oximes with indoles, indole-2-alcohols, or indole-2-carboxmides provides facile access to polysubstituted 3-pyrrolin-2-ones. The reaction features the generation of two adjacent elec

Copper-Catalyzed Dehydrogenative Diels-Alder Reaction

A practical and effective copper-catalyzed dehydrogenative Diels-Alder reaction of gem-diesters and ketone with dienes has been established. The active dienophiles were generated in situ via a radical-based dehydrogenation process, which reacted with a wide variety of dienes to afford various polysubstituted cyclohexene derivatives in good to excellent yields.

Synthesis of vinyldihydropyran by cooperative catalysis

Δ5-Unsaturated aldehydes with a suitably positioned allylic halide, or phosphate, leaving group undergo doubly-catalyzed cyclization to give dihydropyran derivatives. The cyclization proceeds under the synergetic action of diazabicycloundecene and Pd(PPh3)4. This type of transformation was also accomplished with an aryl ketone.