94052-40-1Relevant articles and documents
One-pot synthesis of 2,5-disubstituted pyrimidines from nitriles
Frutos, Rogelio P.,Wei, Xudong,Patel, Nitinchandra D.,Tampone, Thomas G.,Mulder, Jason A.,Busacca, Carl A.,Senanayake, Chris H.
, p. 5800 - 5803 (2013/07/25)
A practical, one-step process for the synthesis of 2,5-disubstituted pyrimidines is presented. The protocol proved to be general for the synthesis of a variety of pyrimidine-containing compounds bearing an assortment of functional groups.
A facile and versatile route to 2-substituted-4(3H)-quinazolinones and quinazolines
Connolly,Guiry
, p. 1707 - 1710 (2007/10/03)
A range of 2-aryl and 2-alkyl quinazolinones have been prepared in moderate to good yields from the reaction of anthranilic acid and the appropriately substituted imidate in a facile, mild, onepot procedure. Subsequent reaction with phosphorus oxychloride afforded the corresponding 4-chloro-2-substituted quinazolines, which are useful synthetic intermediates, in good to high yields. Product isolation was facilitated by the development of work up procedures for both reactions that did not include purification by column chromatography.
Heterocyclic amplifiers of phleomycin. IV. Pyrimidinylpurines, phenylpyrimidines and related systems with basic side chains
Brown,Lan,Mori
, p. 2093 - 2101 (2007/10/02)
-